>>Signaling Pathways>> Apoptosis>> PD-1/PD-L1 interaction>>(D)-PPA 1 TFA

(D)-PPA 1 TFA

Catalog No.GC69009

(D)-PPA 1 TFA는 수해되지 않는 D 펩타이드 억제제입니다. (D)-PPA 1 TFA는 유효한 PD-1/PD-L1 억제제입니다. (D)-PPA 1 TFA의 PD-1 결합 친화력은 0.51 μM이며 체내외에서 모두 효과적입니다.

Products are for research use only. Not for human use. We do not sell to patients.

(D)-PPA 1 TFA Chemical Structure

Size 가격 재고 수량
1mg
US$108.00
재고 있음
5mg
US$270.00
재고 있음
10mg
US$405.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Chemical Properties of (D)-PPA 1 TFA

Cas No. SDF
Formula C72H99F3N20O23 M.Wt 1669.67
Solubility H2O : 100 mg/mL (59.89 mM; Need ultrasonic) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of (D)-PPA 1 TFA

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 0.5989 mL 2.9946 mL 5.9892 mL
5 mM 0.1198 mL 0.5989 mL 1.1978 mL
10 mM 0.0599 mL 0.2995 mL 0.5989 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of (D)-PPA 1 TFA

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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리뷰

Review for (D)-PPA 1 TFA

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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