>>Signaling Pathways>> Stem Cell>> Wnt/β-catenin>>(E)-Ferulic acid-d3

(E)-Ferulic acid-d3 (Synonyms: (E)-Coniferic acid-d3)

Catalog No.GC66371

(E)-페룰산-d3((E)-코니페린산-d3)는 중수소 표지된 (E)-페룰산이다. 821d96072c2d58d8970e76f526b0f6b8(E)-페룰산은 식물 세포벽에 풍부한 방향족 화합물인 페룰산의 이성질체입니다. 821d96072c2d58d8970e76f526b0f6b8(E)-Ferulic acid는 β-카테닌의 인산화를 일으켜 β-카테닌의 프로테아좀 분해를 일으키고 pro-apoptotic factor Bax의 발현을 증가시키고 pro-survival factor survivin의 발현을 감소시킨다. 821d96072c2d58d8970e76f526b0f6b8(E)-Ferulic acid는 활성 산소종(ROS)을 제거하는 강력한 능력을 보여주고 지질 과산화를 억제합니다. 821d96072c2d58d8970e76f526b0f6b8(E)-페룰산은 인간 폐암 세포주 H1299에서 항증식 및 항이동 효과를 발휘합니다.821d96072c2d58d8970e76f526b0f6b8

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(E)-Ferulic acid-d3 Chemical Structure

Cas No.: 860605-59-0

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5mg
US$756.00
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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

(E)-Ferulic acid-d3 ((E)-Coniferic acid-d3) is the deuterium labeled (E)-Ferulic acid. (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Chemical Properties

Cas No. 860605-59-0 SDF Download SDF
Synonyms (E)-Coniferic acid-d3
Formula C10H7D3O4 M.Wt 197.2
Solubility Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 5.071 mL 25.355 mL 50.7099 mL
5 mM 1.0142 mL 5.071 mL 10.142 mL
10 mM 0.5071 mL 2.5355 mL 5.071 mL
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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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