>>Signaling Pathways>> PI3K/Akt/mTOR Signaling>> GSK-3>>(E/Z)-GSK-3β inhibitor 1

(E/Z)-GSK-3β inhibitor 1

Catalog No.GC62736

(E/Z)-GSK-3β 억제제 1은 (E)-GSK-3β의 라세미 화합물이고; 억제제 1 및 (Z)-GSK-3β 억제제 1 이성질체.

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(E/Z)-GSK-3β inhibitor 1 Chemical Structure

Cas No.: 3367-88-2

Size 가격 재고 수량
10mM (in 1mL DMSO)
US$139.00
재고 있음
5 mg
US$126.00
재고 있음
10 mg
US$203.00
재고 있음
50 mg
US$608.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

(E/Z)-GSK-3β inhibitor 1 is a racemic compound of (E)-GSK-3β inhibitor 1 and (Z)-GSK-3β inhibitor 1 isomers. GSK-3β inhibitor 1 (compound 3a) is a glycogen synthase kinase 3β (GSK-3β) inhibitor and demonstrates high antidiabetic efficacy, with an IC50 of 4.9 nM[1].

[1]. Lozinskaya NA, et al. Synthesis and biological evaluation of 3-substituted 2-oxindole derivatives as new glycogen synthase kinase 3β inhibitors. Bioorg Med Chem. 2019 May 1;27(9):1804-1817.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 34 reference(s) in Google Scholar.)

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