>>Signaling Pathways>> Immunology/Inflammation>> FAP>>FT-FAPI-12_9

FT-FAPI-12_9

Catalog No.GC74072

FT-FAPI-12_9 FAP 표적 방사성 추적제 FAPI-46을 합성하는 데 사용할 수 있습니다.

Products are for research use only. Not for human use. We do not sell to patients.

FT-FAPI-12_9 Chemical Structure

Cas No.: 2883407-81-4

Size 가격 재고
5 mg
US$153.00
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10 mg
US$252.00
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25 mg
US$504.00
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Tel:(909) 407-4943 Email: sales@glpbio.com


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Sample solution is provided at 25 µL, 10mM.

Description of FT-FAPI-12_9

FT-FAPI-12_9 is a FAP-binding moiety, which can be used for synthesis of FAP-targeted radiotracer FAPI-46 .

References:
[1]. Jaafar Thiel, et al., Fibroblast activation protein (fap) inhibitors, fap conjugates, and diagnostic and therapeutic uses thereof. WO2024064968 A1

Chemical Properties of FT-FAPI-12_9

Cas No. 2883407-81-4 SDF
Formula C25H31F2N7O2 M.Wt 499.56
Solubility DMSO : 125 mg/mL (250.22 mM; Need ultrasonic and warming) Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of FT-FAPI-12_9

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.0018 mL 10.0088 mL 20.0176 mL
5 mM 0.4004 mL 2.0018 mL 4.0035 mL
10 mM 0.2002 mL 1.0009 mL 2.0018 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of FT-FAPI-12_9

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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리뷰

Review for FT-FAPI-12_9

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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