>>Signaling Pathways>> Others>>(2S)-2'-Methoxykurarinone

(2S)-2'-Methoxykurarinone (Synonyms: 2'-O-Methylkurarinone)

Catalog No.GC34970

Sophora flavescens의 뿌리에서 분리된 화합물인 (2S)-2'-Methoxykurarinone은 항염, 해열, 항당뇨 및 항종양 효과가 있습니다.

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(2S)-2'-Methoxykurarinone Chemical Structure

Cas No.: 270249-38-2

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

(2S)-2'-Methoxykurarinone, a compound isolated from the roots of Sophora flavescens, has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone (MK) inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. (2S)-2'-Methoxykurarinone (MK) displays cytotoxic activity against human myeloid leukemia HL-60 cells[1][2].

[1]. Kim JY, et al. (2S)-2'-Methoxykurarinone inhibits osteoclastogenesis and bone resorption through down-regulation of RANKL signaling. Biol Pharm Bull. 2014;37(2):255-61. [2]. Kang TH, et al. Cytotoxic lavandulyl flavanones from Sophora flavescens. J Nat Prod. 2000 May;63(5):680-1.

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