(E)-Flavokawain A (Synonyms: Flavokavain A, 4-methoxy Flavokawain B) |
Catalog No.GC34981 |
(E)-Flavokawain A, Kava에서 추출한 찰콘은 항암 효과가 있습니다. (E)-플라보카와인 A는 bax 단백질 의존성 및 미토콘드리아 의존성 세포자멸 경로의 관여에 의해 방광암 세포에서 세포자멸사를 유도하고 마우스에서 종양 성장을 억제합니다.
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Cas No.: 37951-13-6
Sample solution is provided at 25 µL, 10mM.
(E)-Flavokawain A, a chalcone extracted from Kava, has anticarcinogenic effect. (E)-Flavokawain A induces apoptosis in bladder cancer cells by involvement of bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice[1].
[1]. Zi X, et al. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. Cancer Res. 2005 Apr 15;65(8):3479-86.
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