1-Cinnamoylpyrrolidine |
Catalog No.GC35064 |
Piper caninum에서 추출한 조추출물인 1-Cinnamoylpyrrolidine(화합물 3)은 DNA 가닥 절단제로 supercoiled pBR322 플라스미드 DNA의 이완을 유도합니다.
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Cas No.: 52438-21-8
Sample solution is provided at 25 µL, 10mM.
1-Cinnamoylpyrrolidine (Compound 3), a crude extract prepared from Piper caninum, is a DNA strand scission agent, induces the relaxation of supercoiled pBR322 plasmid DNA[1].1-Cinnamoylpyrrolidine (Compound 4) inhibits platelet aggregation induced by PAF with an IC50 of 37.3 μM[2]. IC50: 37.3 μM (1-Cinnamoylpyrrolidine)[2]
[1]. Send toBioorg Med Chem.Ma J, et al. Phenolic acid amides: a new type of DNA strand scission agent from Piper caninum. Bioorg Med Chem. 2004 Jul 15;12(14):3885-9. [2]. Chen IS, et al. Amides with anti-platelet aggregation activity from Piper taiwanense. Fitoterapia. 2007 Sep;78(6):414-9. Epub 2007 May 24.
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