2,2,5,7,8-Pentamethyl-6-Chromanol |
| Catalog No.GC35069 |
2,2,5,7,8-Pentamethyl-6-Chromanol(PMC)은 비타민 E(α-토코페롤)의 항산화 성분입니다. 2,2,5,7,8-Pentamethyl-6-Chromanol은 전립선암 세포주에 대해 강력한 안드로겐 수용체(AR) 신호 조절 및 항암 활성을 가지고 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 950-99-2
Sample solution is provided at 25 µL, 10mM.
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2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol). 2,2,5,7,8-Pentamethyl-6-Chromanol has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines[1].
[1]. Kyriakopoulos CE, et al. A multicenter phase 1/2a dose-escalation study of the antioxidant moiety of vitamin E 2,2,5,7,8-pentamethyl-6-chromanol (APC-100) in men with advanced prostate cancer. Invest New Drugs. 2016 Apr;34(2):225-30.
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