>>Peptides>>Atrial Natriuretic Peptide (ANP) (1-28), rat TFA

Atrial Natriuretic Peptide (ANP) (1-28), rat TFA (Synonyms: Atrial natriuretic factor (1-28) (rat) TFA)

Catalog No.GC35426

ANP(Atrial Natriuretic Peptide)(1-28), 쥐(TFA)는 쥐에서 ANP의 주요 순환 형태이며 농도 의존적 방식으로 안지오텐신 II(Ang II) 자극 엔도텔린-1 분비를 강력하게 억제합니다.

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Atrial Natriuretic Peptide (ANP) (1-28), rat TFA Chemical Structure

Size 가격 재고 수량
500μg
US$167.00
재고 있음
1mg
US$260.00
재고 있음
5mg
US$908.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Atrial Natriuretic Peptide (ANP) (1-28), rat (TFA) is a major circulating form of ANP in rats, potently inhibits Angiotensin II (Ang II)-stimulated endothelin-1 secretion in a concentration-dependent manner. Endothelin-1[1]

Rat ANP (1-28) and rat BNP-45, which are the respective major circulating forms of ANP and BNP in rats, potently inhibited Ang II-stimulated endothelin-1 secretion in a concentration-dependent manner. Rat ANP (5-25) is less effective that Rat ANP(1-28) with respect to inhibiting immunoreactive (ir)-endothelin-1 secretion and increasing cellular cyclic GMP. Rat ANP (1-28) inhibits the secretion of ir-endothelin-1 in a concentration-dependent manner between 0.01 and 1 μM[1].

[1]. Kohno M, et al. Angiotensin II stimulates endothelin-1 secretion in cultured rat mesangial cells. Kidney Int. 1992 Oct;42(4):860-6.

Chemical Properties

Cas No. SDF
Synonyms Atrial natriuretic factor (1-28) (rat) TFA
Formula C130H206N45F3O41S2 M.Wt 3176.43
Solubility Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 0.3148 mL 1.5741 mL 3.1482 mL
5 mM 0.063 mL 0.3148 mL 0.6296 mL
10 mM 0.0315 mL 0.1574 mL 0.3148 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Average Rating: 5 ★★★★★ (Based on Reviews and 1 reference(s) in Google Scholar.)

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