Protein Kinase C 19-31 (Synonyms: PKC (19-31)) |
| Catalog No.GC37014 |
PKCa의 유사 기질 조절 도메인(잔기 19-31)에서 유래한 단백질 키나제 C(PKC)의 펩티드 억제제인 \u200b\u200b단백질 키나제 C 19-31은 위치 25에서 야생형 알라닌을 대체하는 세린으로 사용됩니다. protein kinase C 활성을 테스트하기 위한 protein kinase C 기질 펩타이드.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 121545-65-1
Sample solution is provided at 25 µL, 10mM.
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Protein Kinase C (19-31), a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is used as protein kinase C substrate peptide for testing the protein kinase C activity. Protein kinase C (PKC) is involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins[1][2].
[1]. Mellor H, et al. The extended protein kinase C superfamily. Biochem J. 1998 Jun 1;332 ( Pt 2):281-92. [2]. Nishizuka Y (1995). Protein kinase C and lipid signaling for sustained cellular responses" (abstract). FASEB J. 9 (7): 484-96.
| Cas No. | 121545-65-1 | SDF | |
| Synonyms | PKC (19-31) | ||
| Formula | C67H118N26O16 | M.Wt | 1543.82 |
| Solubility | Soluble in DMSO | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 647.7 μL | 3.2387 mL | 6.4774 mL |
| 5 mM | 129.5 μL | 647.7 μL | 1.2955 mL |
| 10 mM | 64.8 μL | 323.9 μL | 647.7 μL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
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Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
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- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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