HBC620 |
Catalog No.GC60186 |
HBC620는 HBC의 아날로그로, 구조적으로 강한 전자 기부체와 구조적으로 단단한 전자 수용체를 가진 GFP 형광효소와 유사한 합성 염료입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2530162-07-1
Sample solution is provided at 25 µL, 10mM.
HBC620 is an analog of HBC, which is a GFP fluorophore-like synthetic dye with a structurally rigid electron acceptor and a strong electron donor. HBC is nonfluorescent in solution, but strongly fluoresces upon constraining intramolecular motion. HBC-Pepper complex can be used to visualize RNA dynamics in live cells[1].
HBC's fluorescence can be enhanced more than 3000-fold in vitro by Pepper. Mammalian cells expressing Pepper exhibited robust greenyellowish fluorescence on incubation with 1μM HBC[1].
References:
[1].Chen X, Zhang D, et al. Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs. Nat Biotechnol. 2019;37(11):1287-1293.
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