>>Signaling Pathways>> GPCR/G protein>> Melatonin Receptors>>Melatonin-d3

Melatonin-d3 (Synonyms: N-Acetyl-5-methoxytryptamine-d3)

Catalog No.GC69448

Melatonin-d3는 멜라토닌의 대위원소입니다. 멜라토닌은 잉태선에서 생성되는 호르몬으로, 타이로신을 전구체로 하여 합성됩니다. 멜라토닌은 수면에 영향을 주며 중요한 항산화 및 항염 특성을 가지고 있습니다. 또한 새로운 선택적 ATF-6 억제제이며 COX-2를 통해 유도된 인간 간암 세포의 세포사멸을 유도합니다. 멜라토닌은 내부망 스트레스를 완화하여 팔미트산 유도 마우스 입자세포 사멸을 줄일 수 있습니다.

Products are for research use only. Not for human use. We do not sell to patients.

Melatonin-d3 Chemical Structure

Cas No.: 90735-69-6

Size 가격 재고 수량
10mg
US$342.00
재고 있음
25mg
US$684.00
재고 있음
50mg
US$1,098.00
재고 있음

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고객 리뷰

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.

Chemical Properties of Melatonin-d3

Cas No. 90735-69-6 SDF
Synonyms N-Acetyl-5-methoxytryptamine-d3
Formula C13H13D3N2O2 M.Wt 235.3
Solubility DMSO : 100 mg/mL (424.99 mM; Need ultrasonic) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Melatonin-d3

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 4.2499 mL 21.2495 mL 42.4989 mL
5 mM 850 μL 4.2499 mL 8.4998 mL
10 mM 425 μL 2.1249 mL 4.2499 mL
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In vivo Formulation Calculator (Clear solution) of Melatonin-d3

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents of Melatonin-d3

Quality Control & SDS

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리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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