N,N-Dimethylsphingosine |
| Catalog No.GC16873 |
N,N-디메틸스핑고신은 다양한 조직과 종양 세포주에서 생성되는 스핑고신의 내인성 대사산물인 SphK(스핑고신 키나제)의 강력한 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 119567-63-4
Sample solution is provided at 25 µL, 10mM.
GlpBio Products Cited In Reputable Papers
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Product Documents
Quality Control & SDS
- View current batch:
- Purity: >98.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
| Cas No. | 119567-63-4 | SDF | |
| Chemical Name | (2S,3R,E)-2-(dimethylamino)octadec-4-ene-1,3-diol | ||
| Canonical SMILES | O[C@H](/C=C/CCCCCCCCCCCCC)[C@H](CO)N(C)C | ||
| Formula | C20H41NO2 | M.Wt | 327.55 |
| Solubility | DMF: >65 mg/ml,DMSO: >50 mg/ml,Ethanol: >25 mg/ml,PBS pH 7.2: >2 mg/ml | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
||
| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
Complete Stock Solution Preparation Table
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 3.053 mL | 15.2648 mL | 30.5297 mL |
| 5 mM | 0.6106 mL | 3.053 mL | 6.1059 mL |
| 10 mM | 0.3053 mL | 1.5265 mL | 3.053 mL |
In vivo Formulation Calculator (Clear solution)
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Related Products
- GC11467 AS 2034178
- GC11010 AZD 3965
- GC30832 GSK1059865
- GC32796 ERK5-IN-1
- GC34272 NH2-QGGYTMHQDQEGDTDAGLK-COOH
- GC19557 2,4-Dichlorophenol
- GC43856 Histone H3K4Me2 (1-10) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)
- GC12461 HA-100 (hydrochloride)
- GC61032 MCP110
- GC39259 Laminaran
- GC18791 Prostaglandin H1
- GC30419 ALPS (N-Ethyl-N-sulfopropylaniline sodium salt)
- GC42002 1-Myristoyl-2-hydroxy-sn-glycero-3-PG (sodium salt)
- GC18455 Digoxigenin Monodigitoxoside
- GC31307 4-Methyl-2-oxopentanoic acid
- GC39143 Tetrahydropapaverine hydrochloride
- GC44944 Sporidesmolide I
리뷰
Average Rating: 5 ★★★★★ (Based on Reviews and 40 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *