OVA Peptide (257-264) TFA (Synonyms: Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu, SIINFEKL, OVA (257-264)) |
| Catalog No.GC33600 |
OVA 펩티드(257-264) TFA는 OVA의 클래스 I(Kb)-제한된 펩티드 에피토프이며, 팔량체 펩티드는 클래스 I MHC 분자, H-2Kb에 의해 제시된 오브알부민에서 유래할 수 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1262751-08-5
Sample solution is provided at 25 µL, 10mM.
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OVA Peptide (257-264) TFA is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.
TAP1-I- and C57BL/6 macrophages may process Crl-OVA and full-length OVA in different cellular compartments and that the protein context of the OVA Peptide (257-264) epitope influences the extent of TAP-independent processing for MHC class I presentation. OVA Peptide (257-264) epitope is presented with a differential dependence on the TAP transporter depending on the protein context of the OVA epitope: OVA Peptide (257-264) contained within the MBPCrl-OVA or Crl-OVA bacterial fusion proteins is presented with little dependence on the TAP transporter, while OVA Peptide (257-264) contained within full-length ovalbumin is largely dependent on the TAP transporter, regardless of whether recombinant OVA is expressed in bacteria or the native protein is coupled to polystyrene beads[1].
[1]. Wick MJ, et al. Major histocompatibility complex class I presentation of ovalbumin peptide 257-264 from exogenous sources: protein context influences the degree of TAP-independent presentation. Eur J Immunol. 1996 Nov;26(11):2790-9.
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