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Phoenixin-20

Catalog No.GC72294

Phoenixin-20 (PNX-20)은 척추동물에서 호르몬 유사 작용을 하는 생리활성 펩타이드이며, 시상하부-뇌하수체-성선 호르몬을 자극하고 포유동물의 생식 과정을 조절할 수 있다.

Products are for research use only. Not for human use. We do not sell to patients.

Phoenixin-20 Chemical Structure

Cas No.: 1415039-77-8

Size 가격 재고 수량
1mg
US$72.00
재고 있음
5mg
US$180.00
재고 있음
10mg
US$270.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description of Phoenixin-20

Phoenixin-20 (PNX-20) is a bioactive peptide with hormone-like actions in vertebrates, and can stimulates hypothalamo-pituitary-gonadal hormones and regulate reproductive processes in mammals. Phoenixin-20 promotes neuronal mitochondrial biogenesis via CREB-PGC-1α pathway. Phoenixin-20 has anxiolytic effect.

References:
[1]. Yang Y, et al. Phoenixin 20 promotes neuronal mitochondrial biogenesis via CREB-PGC-1α pathway. J Mol Histol. 2020;51(2):173-181.
[2]. Rajeswari JJ, et al. Phoenixin-20 Stimulates mRNAs Encoding Hypothalamo-Pituitary-Gonadal Hormones, is Pro-Vitellogenic, and Promotes Oocyte Maturation in Zebrafish. Sci Rep. 2020;10(1):6264.
[3]. Jiang JH, et al. Effects of Phoenixin-14 on anxiolytic-like behavior in mice. Behav Brain Res. 2015;286:39-48.

Chemical Properties of Phoenixin-20

Cas No. 1415039-77-8 SDF
Formula C101H153N25O29 M.Wt 2181.45
Solubility DMSO : 50 mg/mL (22.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Storage Sealed storage, away from moisture and light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Phoenixin-20

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 0.4584 mL 2.2921 mL 4.5841 mL
5 mM 0.0917 mL 0.4584 mL 0.9168 mL
10 mM 0.0458 mL 0.2292 mL 0.4584 mL
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In vivo Formulation Calculator (Clear solution) of Phoenixin-20

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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