Phosphatase Inhibitor Cocktail I (100× in DMSO) |
| Catalog No.GK10011 |
인산화효소 억제제 칵테일 I은 알칼리성 인산화효소와 PP1 및 PP2A와 같은 세린/트레오닌 단백질 인산화 효소를 효과적으로 억제합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
- Mol Med 30.1 (2024)：1-14.PMID:38760717
- Int Immunopharmacol 133 (2024)：112130.PMID:38648712
- Biochem Pharmacol (2024)：116230.PMID:38643905
- Int Immunopharmacol 130 (2024)：111750.PMID:38442577
- Food Chem Toxicol 173 (2023)：113640.PMID:36724846
- Ecotox Environ Safe 286 (2024)：117223.PMID:39447291
- J Ethnopharmacol (2023)：117537.PMID:38043756
- Skeletal Muscle 14 (2024).PMID:39026344
- J Hepatocell Carcino (2023)：1639-1657.PMID:37791068
- J Pharm Pharmacol (2024)：rgae060.PMID:38767973
- Acta Bioch Bioph Sin 56.11 (2024)：1673.PMID:39108207
- Acta Bioch Bioph Sin 56.7 (2024)：1022.PMID:38818581
- Adv Funct Mater (2024)：2305827.
- Int Immunopharmacol 116 (2023)：109637.
- Biomedicines 10.10 (2022)：2358.
- J Control Release 372 (2024)：778-794.PMID:38936744
Phosphatase Inhibitor Cocktail I effectively inhibits alkaline phosphatases and serine/threonine protein phosphatases such as PP1 and PP2A.
Phosphorylation of proteins and lipids is a hallmark of the signaling or metabolic status of cells. A cocktail of three inhibitors that will inhibit alkaline phosphatases as well as serine/threonine protein phosphatases such as PP1 and PP2A. Each vial contains 1 ml phosphatase inhibitor cocktail solubilized in DMSO with the following components: Bromotetramisole oxalate (2.5 mM), Cantharidin (500 µM), and Microcystin-LR , Microcystis aeruginosa (500 nM).
Phosphatase Inhibitor Cocktail I has been optimized and tested for mammalian cell and tissue extracts. This cocktail is supplied as a ready-to-use solution in DMSO.
Components
| Ingredient | M.W. | 100x Conc. | Target |
| (-)-p-Bromotetramisole oxalate | 995.2 | 2.5 mM | Alkaline phosphatases |
| Cantharidin | 373.2 | 500 μM | Ser/Thr phosphatases |
| Microcystin LR, Microcystis aeruginosa | 196.2 | 500 nM | PP1 and PP2A |
Thaw at room temperature. Before assaying, add each solution at 1:100 (v/v) dilution to samples (such as cell lysates or tissue extracts). Mix the sample sufficiently after each time of addition.
Application Fields: Western Blot analysis, Co-IP, pull-down, IF, IHC, kinase assay and etc.
- View current batch:
Average Rating: 5 (Based on Reviews and 10 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *