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홈 >> Proteins >> Growth Factors

Growth Factors

Products for  Growth Factors

  1. Cat.No. 상품명 정보
  2. GC48920 β-Carboline-1-carboxylic Acid

    1-Formic Acid-β-carboline

     An alkaloid with diverse biological activities β-Carboline-1-carboxylic Acid Chemical Structure
  3. GC45270 (±)10(11)-EDP Ethanolamide

    10,11-EDP-EA, 10,11-EDP epoxide, 10,11-epoxy Docosapentaenoic Ethanolamide

     (±)10(11)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 0.43 and 22.5 nM for CB1 and CB2 receptors, respectively). (±)10(11)-EDP Ethanolamide Chemical Structure
  4. GC41648 (±)13(14)-DiHDPA

    13(14)-DiHDPA, 13(14)-DiHDoPE, 13,14-DiHDPE

     (±)13(14)-DiHDPA is a metabolite of docosahexaenoic acid that is produced via oxidation by cytochrome P450 epoxygenases. (±)13(14)-DiHDPA Chemical Structure
  5. GC41653 (±)16(17)-DiHDPA (±)16(17)-DiHDPA is produced from cytochrome P450 epoxygenase action on docosahexaenoic acid. (±)16(17)-DiHDPA Chemical Structure
  6. GC41655 (±)19(20)-EDP Ethanolamide

    19,20-DHEA epoxide, 19,20-epoxy Docosapentaenoic Acid Ethanolamide, 19,20-EDP-EA, 19,20-EDP epoxide

     (±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively). (±)19(20)-EDP Ethanolamide Chemical Structure
  7. GC45266 (+)-Macrosphelide A (+)-Macrosphelide A는 macrolide 항생제입니다. (+)-Macrosphelide A Chemical Structure
  8. GC40444 (5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic Acid

    HETE Analog 1, Hydroxyeicosatetraenoic Acid Analog 1

     (5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic acid is a stable isomer of 15(S)-HETE, a major arachidonic acid metabolite from the 15-lipoxygenase pathway. (5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic Acid Chemical Structure
  9. GC41220 13(S)-HODE methyl ester 13(S)-hydroxyoctadecadienoic acid (13(S)-HODE) is a 15-lipoxygenase metabolite of linoleic acid produced in endothelial cells, leukocytes, and tumor cells. 13(S)-HODE methyl ester Chemical Structure
  10. GC46733 7,12-Dimethylbenz[a]anthracene

    DMBA

     7,12-Dimethylbenz[a]anthracene는 면역억제제이자 강력한 장기특이성 발암물질이다. 7,12-Dimethylbenz[a]anthracene Chemical Structure
  11. GC48486 AAA A GPR75 antagonist AAA Chemical Structure
  12. GP20001 Activin-A Human Active Activin-A Human Active Chemical Structure
  13. GC46821 Ajoene 마늘에서 추출한 화합물인 아조엔은 항혈전 및 항진균제입니다. Ajoene Chemical Structure
  14. GC42951 BMP-22 BMP-22 is an inhibitor of autotaxin (IC50 = 170 nM). BMP-22 Chemical Structure
  15. GC42975 BRD32048 BRD32048은 KD가 17.1μM인 ETV1의 직접 결합제입니다. BRD32048은 ETV1이 매개하는 전사 활성과 ETV1에 의해 유도되는 암세포의 침입을 모두 조절합니다. BRD32048은 ETV1 아세틸화를 억제하고 분해를 촉진합니다. BRD32048은 최고 후보 ETV1 perturbagen으로 작동합니다. BRD32048 Chemical Structure
  16. GC48433 BX-320 BX-320은 직접 키나제 분석 형식에서 IC50이 30nM인 선택적 ATP-경쟁적 경구 활성 및 직접 PDK1 억제제입니다. BX-320은 또한 apoptosis를 유도합니다. 항암 효과. BX-320 Chemical Structure
  17. GC43042 C17 Lactosylceramide (d18:1/17:0)

    N-Heptadecanoyl Lactosylceramide, LacCer(d18:1/17:0), Lactosylceramide (d18:1/17:0)

     C17 Lactosylceramide is a naturally occurring sphingolipid that has been found in human brain metastases of lung adenocarcinomas but not in healthy brain tissue. C17 Lactosylceramide (d18:1/17:0) Chemical Structure
  18. GC45403 CAY10735   CAY10735 Chemical Structure
  19. GC47098 CL2-SN-38 (dichloroacetic acid salt) An antibody-drug conjugate containing SN-38 CL2-SN-38 (dichloroacetic acid salt) Chemical Structure
  20. GC43346 Cyclopamine-KAAD 고슴도치 신호 억제제인 Cyclopamine-KAAD는 부드러운 길항제입니다. Cyclopamine-KAAD Chemical Structure
  21. GC43360 Cytostatin Cytostatin은 유망한 항종양 활성을 가진 PP2A의 강력하고 선택적인 억제제입니다. Cytostatin은 또한 세포외 기질에 대한 세포 부착의 억제제이며 세포 사멸을 유도합니다. Cytostatin은 천연 제품의 fosriecin 계열에 속합니다. Cytostatin Chemical Structure
  22. GC43361 Cytostatin (sodium salt) Cytostatin is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50s = 1.3 and 1.4 μg/ml, respectively) and B16 cells metastatic activity in mice. Cytostatin (sodium salt) Chemical Structure
  23. GC45767 Dovitinib-d8 도비티닙-D8(CHIR-258-D8)은 도비티닙으로 표지된 중수소입니다. 도비티닙(CHIR-258)은 FLT3, c-Kit, FGFR1/FGFR3, VEGFR1/VEGFR2/에 대해 IC50이 1, 2, 8/9, 10/13/8, 27/210 nM인 다중 표적 티로신 키나제 억제제입니다. 각각 VEGFR3 및 PDGFRα/PDGFRβ. Dovitinib-d8 Chemical Structure
  24. GC45448 Epitalon (acetate)

    Epithalone

       Epitalon (acetate) Chemical Structure
  25. GP20210 FGF 2 Human

    Fibroblast Growth Factor-Basic Human Recombinant

     FGF 2 Human Chemical Structure
  26. GC43719 Fusarisetin A

    (+)-Fusarisetin A

     5환식 진균 대사산물인 Fusarisetin A는 포상 형태 형성 억제제입니다. Fusarisetin A Chemical Structure
  27. GC43727 Ganglioside GD1a mixture (sodium salt)

    Ganglioside B1

    Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver.

     Ganglioside GD1a mixture (sodium salt) Chemical Structure
  28. GC43729 Ganglioside GD3 Mixture (sodium salt)

    Disialosyllactosylceramide Mixture

     Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases. Ganglioside GD3 Mixture (sodium salt) Chemical Structure
  29. GC43732 Ganglioside GM3 Mixture (sodium salt)

    Hematoside, Monosialoganglioside GM1, Sialosyllactosylceramide

     Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation. Ganglioside GM3 Mixture (sodium salt) Chemical Structure
  30. GC47398 Genistein-d4 Genistein-d4(NPI 031L-d4)는 Genistein으로 표시된 중수소입니다. 대두 이소플라본인 제니스테인은 주로 세포자멸사, 세포 주기 및 혈관신생을 변경하고 전이를 억제함으로써 다양한 유형의 암에 대한 화학요법제로 작용하는 다중 티로신 키나제(예: EGFR) 억제제입니다. Genistein-d4 Chemical Structure
  31. GC47400 GGTI 2133 (trifluoroacetate salt) A geranylgeranyl transferase I inhibitor GGTI 2133 (trifluoroacetate salt) Chemical Structure
  32. GC43780 GM 1489 GM 1489 is a broad-spectrum inhibitor of matrix metalloproteinases (MMPs) with Ki values of 0.002, 0.1, 0.5, 0.2, and 20 μM for MMP-1, MMP-8, MMP-2, MMP-9, and MMP-3, respectively. GM 1489 Chemical Structure
  33. GP20372 HGF Human

    Hepatocyte Growth Factor Human Recombinant

     HGF Human Chemical Structure
  34. GC74474 Imalumab

    BAX69; Anti-Human MIF Recombinant Antibody

     Imalumab (BAX69)는 대식세포 억제인자 (MIF)를 표적으로 하는 재조합, 인간 IgG1단일클론 항체이다. Imalumab Chemical Structure
  35. GC48387 Inostamycin A A bacterial metabolite with anticancer activity Inostamycin A Chemical Structure
  36. GC47459 Irinotecan-d10 (hydrochloride)

    Camptothecin 11-d10, CPT 11- d10, Topotecin-d10, U 101440E-d10

     이리노테칸-d10((+)-이리노테칸-d10) 염산염은 이리노테칸으로 표시된 중수소입니다. 이리노테칸((+)-Irinotecan)은 토포이소머라제 I-DNA 복합체에 결합하여 DNA 가닥의 재연결을 방지하는 토포이소머라제 I 억제제입니다. Irinotecan-d10 (hydrochloride) Chemical Structure
  37. GC18909 KRIBB3

    KRIBB3 is an Hsp27 and microtubule inhibitor that inhibits migration and invasion of MDA-MB-231 cells in vitro in an Hsp27-dependent manner.

     KRIBB3 Chemical Structure
  38. GC46015 KY 05009 KY 05009는 100nM의 Ki를 갖는 ATP-경쟁적 Traf2 및 Nck-상호작용 키나제(TNIK) 억제제입니다. KY 05009는 인간 폐 선암종 세포에서 TGF-β1에 의해 유도된 상피에서 중간엽으로의 전이(EMT)를 약리학적으로 억제합니다. KY 05009는 TNIK의 단백질 발현과 Wnt 표적 유전자의 전사 활성을 억제하고 암세포에서 세포 사멸을 유도합니다. KY 05009는 항암 활성을 나타냅니다. KY 05009 Chemical Structure
  39. GC47582 Lupulone Lupulone은 홉 식물 H.의 베타산입니다. Lupulone Chemical Structure
  40. GC48479 Migrastatin

    (+)-Migrastatin

     A fungal metabolite with antimuscarinic and anticancer activities Migrastatin Chemical Structure
  41. GC44222 ML-298 ML298은 355nM의 IC50을 갖는 포스포리파제 D2(PLD2)의 강력하고 선택적인 억제제입니다. ML298은 U87-MG 교모세포종 세포에서 침습적 이동을 감소시킵니다. ML-298 Chemical Structure
  42. GC44223 ML-299

    CID 56593087

     ML-299는 선택적 알로스테릭 조절제이자 포스포리파제 D1 및 D2의 이중 억제제입니다(IC50 값은 각각 6 및 12 nM임). ML-299는 U87-MG 교모세포종 세포에서 침습적 이동을 감소시킵니다. ML-299 Chemical Structure
  43. GC18608 MMP-2/MMP-9 Inhibitor II

    Matrix Metalloproteinase-2/Matrix Metalloproteinase-9 Inhibitor II

     MMP-2/MMP-9 inhibitor II is a dual inhibitor of matrix metalloproteinase-2 (MMP-2) and MMP-9 (IC50s = 17 and 30 nM, respectively). MMP-2/MMP-9 Inhibitor II Chemical Structure
  44. GC18612 MMP-9/MMP-13 Inhibitor I

    Matrix Metalloproteinase-9/Matrix Metalloproteinase-13 Inhibitor I

     MMP-9/MMP-13 inhibitor I is a cell-permeable inhibitor of matrix metalloproteinases (MMPs) that most potently inhibits MMP-9 and MMP-13 (IC50s = 0.9 nM for both). MMP-9/MMP-13 Inhibitor I Chemical Structure
  45. GC47720 N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine A microbial metabolite with anticancer activity N,N'-bis(2,3-Dihydroxybenzoyl)-O-L-seryl-L-serine Chemical Structure
  46. GC44313 Naphthofluorescein

    CCG 8295

     Naphthofluorescein은 HIF-1과 Mint3 간의 상호 작용을 억제합니다. Naphthofluorescein은 시험관 내 세포 독성 및 생체 내 부작용 없이 암세포와 대식세포에서 Mint3 의존적 HIF-1 활성 및 해당 작용을 억제합니다. Naphthofluorescein은 또한 기능적인 Cerenkov 이미징에 사용할 수 있는 형광 pH 민감성 프로브입니다. Naphthofluorescein Chemical Structure
  47. GC44387 Neurotensin (trifluoroacetate salt) Neurotensin is a neuropeptide that is distributed throughout the CNS and in enteroendocrine cells of the small intestine that has diverse biological activities. Neurotensin (trifluoroacetate salt) Chemical Structure
  48. GC48839 Nifuroxazide-d4 An internal standard for the quantification of nifuroxazide Nifuroxazide-d4 Chemical Structure
  49. GC45760 Nilutamide-d6 Nilutamide-d6(Nilandron-d6)은 Nilutamide로 표시된 중수소입니다. Nilutamide(Nilandron)는 전이성 전립선암 연구에서 제안된 비스테로이드성 항안드로겐 약물입니다. Nilutamide-d6 Chemical Structure
  50. GC48788 Norethindrone-d6

    Norethisterone-d6

     An internal standard for the quantification of norethindrone Norethindrone-d6 Chemical Structure
  51. GC46018 Norstictic Acid Norstictic acid는 강력하고 선택적인 allossteric 전사 조절 인자입니다. Norstictic Acid Chemical Structure
  52. GC44518 Osteocalcin (1-49) (human) (trifluoroacetate salt) Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Osteocalcin (1-49) (human) (trifluoroacetate salt) Chemical Structure
  53. GC44545 Palmitoleoyl 3-carbacyclic Phosphatidic Acid

    3carbacyclic PA, 3ccPA 16:1

     Cyclic phosphatidic acids (cPAs) are naturally occurring analogs of lysophosphatidic acid (LPA) in which the sn-2 hydroxy group forms a 5-membered ring with the sn-3 phosphate. Palmitoleoyl 3-carbacyclic Phosphatidic Acid Chemical Structure
  54. GC45777 Peonidin 3-O-glucoside (chloride)

    Peonidin 3-β-D-glucopyranoside

     안토시아닌인 Peonidin 3-O-glucoside(chloride)는 인슐린 분비 촉진제 역할을 합니다. Peonidin 3-O-glucoside (chloride) Chemical Structure
  55. GC47955 Phloroglucinol

    Benzene-s-triol, 1,3,5-Hydroxybenzene, NSC 1572, 1,3,5-Trihydroxybenzene, sym-Trihydroxybenzene

     A phenol with diverse biological activities Phloroglucinol Chemical Structure
  56. GC47963 Plerixafor-d4 An internal standard for the quantification of plerixafor Plerixafor-d4 Chemical Structure
  57. GC44782 PX-866-17OH A PI3K inhibitor PX-866-17OH Chemical Structure
  58. GC45554 Questiomycin A   Questiomycin A Chemical Structure
  59. GC18751 Reticulol

    6,8-dihydroxy-7-methoxy-3-methyl Isocoumarin, NSC 294978

     Reticulol is an isocoumarin derivative produced by certain species of Streptomyces that inhibits cAMP phosphodiesterase (IC50 = 41 uM). Reticulol Chemical Structure
  60. GC44847 RKI-1313 RKI-1313은 ROCK 1 및 ROCK 2에 대해 IC50이 각각 34, 8μM인 ROCK 억제제입니다. RKI-1313은 ROCK 기질의 인산화 수준, 이동, 침입 또는 앵커리지 독립적 성장에 거의 영향을 미치지 않습니다. RKI-1313 Chemical Structure
  61. GC40285 Rubratoxin A

    BRN 1633008, HSDB 3532

     루브라톡신 A는 천연 진균독이며 170nM의 IC50을 갖는 단백질 포스파타제 2A(PP2A)의 경쟁적 억제제입니다. 루브라톡신 A는 마우스 이종이식편에서 종양 전이의 억제 및 원발성 종양 부피의 감소를 유발합니다. Rubratoxin A Chemical Structure
  62. GP20923 SCF Mouse Stem Cell Factor Mouse Recombinant SCF Mouse Chemical Structure
  63. GC40069 Teleocidin A1

    Lyngbyatoxin A

     고독성 피부 자극제인 텔레오시딘 A1(Lyngbyatoxin A)은 단백질 키나제 C(PKC)의 강력한 활성제입니다. Teleocidin A1은 HeLa 암세포에 대한 항증식 활성을 나타냅니다(IC50=9.2nM). Teleocidin A1 Chemical Structure
  64. GP20944 TGFB1 Human

    TGF-β1 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-β1 superfamily that share a characteristic cystine knot structure.

     TGFB1 Human Chemical Structure
  65. GC48659 Umbelliprenin

    7-Farnesyloxycoumarin

     A prenylated coumarin with diverse biological activities Umbelliprenin Chemical Structure
  66. GC45769 Vandetanib-d6

    ZD6474-d6

     반데타닙-d6(ZD6474-d6)은 반데타닙으로 표시된 중수소입니다. 반데타닙(D6474)은 VEGFR2/KDR 티로신 키나제 활성(IC50=40nM)의 강력한 경구 활성 억제제입니다. 반데타닙은 또한 VEGFR3/FLT4(IC50=110nM) 및 EGFR/HER1(IC50=500nM)의 티로신 키나제 활성 대 활성을 갖는다. Vandetanib-d6 Chemical Structure

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