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홈 >> Signaling Pathways >> Apoptosis >> Pyroptosis

Pyroptosis

Products for  Pyroptosis

  1. Cat.No. 상품명 정보
  2. GA20494 Ac-Asp-Glu-Val-Asp-pNA

    Ac-Asp-Glu-Val-Asp-pNA

     The cleavage of the chromogenic caspase-3 substrate Ac-DEVD-pNA can be monitored at 405 nm. Ac-Asp-Glu-Val-Asp-pNA Chemical Structure
  3. GC48470 Ac-DEVD-CHO (trifluoroacetate salt)

    N-Ac-Asp-Glu-Val-Asp-CHO

     A dual caspase3/caspase7 inhibitor Ac-DEVD-CHO (trifluoroacetate salt) Chemical Structure
  4. GC65107 Ac-FEID-CMK TFA Ac-FEID-CMK TFA는 강력한 제브라피쉬 특이적 GSDMEb 유래 펩타이드 억제제입니다. Ac-FEID-CMK TFA Chemical Structure
  5. GC60558 Ac-FLTD-CMK Gasdermin D(GSDMD) 유래 억제제인 Ac-FLTD-CMK는 특정 염증성 카스파제 억제제입니다. Ac-FLTD-CMK Chemical Structure
  6. GC49704 Ac-FLTD-CMK (trifluoroacetate salt)

    Ac-Phe-Leu-Thr-Asp-CMK

     An inhibitor of caspase-1, -4, -5, and -11 Ac-FLTD-CMK (trifluoroacetate salt) Chemical Structure
  7. GC42708 Ac-LEHD-AFC (trifluoroacetate salt)

    N-Acetyl-Leu-Glu-His-Asp-7-amino-4-Trifluoromethylcoumarin, Caspase-9 substrate (Fluorogenic)

     Ac-LEHD-AFC is a fluorogenic substrate that can be cleaved by caspase-4, -5, and -9. Ac-LEHD-AFC (trifluoroacetate salt) Chemical Structure
  8. GC42709 Ac-LEVD-CHO (trifluoroacetate salt)

    Ac-Leu-Glu-Val-Asp-CHO, Caspase-4 Inhibitor I

    Ac-LEVD-CHO is a caspase-4 inhibitor.

     Ac-LEVD-CHO (trifluoroacetate salt) Chemical Structure
  9. GC40124 Ac-WEAD-AMC (trifluoroacetate salt)

    Ac-Trp-Glu-Ala-Asp-AMC

     Ac-WEAD-AMC is a fluorogenic substrate for caspase-1 and caspase-4. Ac-WEAD-AMC (trifluoroacetate salt) Chemical Structure
  10. GC42719 Ac-WEAD-pNA (trifluoroacetate salt)

    Ac-Trp-Glu-Ala-Asp-pNA, Ac-Trp-Glu-Ala-Asp-p-nitroanilide, Caspase-1 and Caspase-4 Chromogenic Substrate

     Ac-WEAD-pNA is a colorimetric substrate for caspase-1 and caspase-4. Ac-WEAD-pNA (trifluoroacetate salt) Chemical Structure
  11. GC46796 Ac-WEHD-AFC (trifluoroacetate salt)

    N-Acetyl-Trp-Glu-His-Asp-7-amino-4-Trifluoromethylcoumarin, Caspase1 Substrate (Fluorogenic), Caspase5 Substrate (Fluorogenic)

     A neuropeptide with diverse biological activities Ac-WEHD-AFC (trifluoroacetate salt) Chemical Structure
  12. GC18021 Ac-YVAD-CHO

    Caspase-1 Inhibitor I, L 709049, N-Ac-Tyr-Val-Ala-Asp-CHO

     Ac-YVAD-CHO(L-709049)는 3.0 및 0.76nM의 마우스 및 인간 Ki 값을 갖는 강력하고 가역적인 특이적 테트라펩타이드 인터루킨-1β 전환 효소(ICE) 억제제입니다. Ac-YVAD-CHO Chemical Structure
  13. GC42721 Ac-YVAD-CMK

    N-Ac-Tyr-Val-Ala-Asp-CMK

     Ac-YVAD-CMK 되돌 릴 수 없는 선택적 억제 제야의 caspase-1 (Ki=0.8nM), proinflammatory을 방지 할 수 있는 사이토 카인 IL-1 β 활성화다.Ac-YVAD-CMK는 염증 반응을 줄이고 오래 지속되는 신경 보호 효과를 유도할 수 있다. Ac-YVAD-CMK Chemical Structure
  14. GC40149 Boc-AEVD-CHO (trifluoroacetate salt)

    Boc-Ala-Glu-Val-Asp-CHO

     Boc-AEVD-CHO is an inhibitor of caspase-8 (Ki = 1.6 nM) that also inhibits caspase-1, -3, -6, and -9 (Kis = 10,000, 375, 438, 425, and 320 nM, respectively). Boc-AEVD-CHO (trifluoroacetate salt) Chemical Structure
  15. GC18421 Dabcyl-YVADAPV-EDANS

    Dabcyl-ICE-EDANS

     Dabcyl-YVADAPV-EDANS is a fluorogenic substrate for caspase-1. Dabcyl-YVADAPV-EDANS Chemical Structure
  16. GC91060 Ferritin PROTAC DeFer-2

    페리틴 분해를 유도하는 PROTAC

     Ferritin PROTAC DeFer-2 Chemical Structure
  17. GC43668 FITC-C6-YVADAP-K(Dnp) (trifluoroacetate salt)

    FITC-C6-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH

     FITC-C6-YVADAP-K(Dnp) is a caspase-1 fluorogenic substrate. FITC-C6-YVADAP-K(Dnp) (trifluoroacetate salt) Chemical Structure
  18. GC74070 INF 195 INF 195NLRP3 억제제의 일종입니다. INF 195 Chemical Structure
  19. GC65393 LDC7559 LDC7559는 후기 단계에서 호중구 세포외 트랩(NET) 차단을 통해 가스더민 D(GSDMD) 억제제입니다. LDC7559 Chemical Structure
  20. GC40120 Mca-LEVDGW-K(Dnp)-NH2 (trifluoroacetate salt)

    Mca-Leu-Glu-Val-Asp-Gly-Trp-Lys(Dnp)-NH2

     Mca-LEVDGW-K(Dnp)-NH2 is a fluorogenic substrate for caspase-4. Mca-LEVDGW-K(Dnp)-NH2 (trifluoroacetate salt) Chemical Structure
  21. GC47607 Mca-YVADAP-K(Dnp)-OH (trifluoroacetate salt)

    Caspase-1 Fluorogenic Substrate V, Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(DNP)-OH, Mca-YVADAP-Lys(Dnp)-OH, (7-Methoxycoumarin-4-yl)acetyl-YVADAPK(2,4-dinitrophenyl)-OH

     A neuropeptide with diverse biological activities Mca-YVADAP-K(Dnp)-OH (trifluoroacetate salt) Chemical Structure
  22. GC49681 Necrosulfonamide-d4

    NSA-d4

     Necrosulfonamide-d4는 Necrosulfonamide로 표시된 중수소입니다. Necrosulfonamide는 MLKL(mixed lineage kinase domain-like protein)을 선택적으로 표적화하여 작용하는 괴사 억제제입니다. Necrosulfonamide는 MLKL-RIP1-RIP3 necrosome 복합체가 다운스트림 이펙터와 상호 작용하는 것을 방지합니다. MLKL은 괴사 유도 동안 RIP3의 중요한 기질입니다. Necrosulfonamide-d4 Chemical Structure
  23. GC49024 Palmitic Acid MaxSpec® Standard

    C16:0, Cetylic Acid, NSC 5030

     A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Palmitic Acid MaxSpec® Standard Chemical Structure
  24. GC49023 Palmitic Acid-d9 MaxSpec® Standard

    C16:0-d9, Cetylic Acid-d9

     A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Palmitic Acid-d9 MaxSpec® Standard Chemical Structure
  25. GC72191 Pep19-2.5 Pep19-2.5는 합성 및 항독소 펩타이드로, 세포 내 독소 신호 폭주를 차단합니다. Pep19-2.5 Chemical Structure
  26. GC44967 Suc-YVAD-AMC (acetate)

    Suc-Tyr-Val-Ala-Asp-AMC, Suc-Tyr-Val-Ala-Asp-7-amino-4-methylcoumarin, Suc-YVAD-NH-Mec

     Suc-YVAD-AMC is a fluorogenic substrate for caspase-1. Suc-YVAD-AMC (acetate) Chemical Structure
  27. GC45175 YVAD-CHO (trifluoroacetate salt)

    H-Tyr-Val-Ala-Asp-CHO

     YVAD-CHO is an inhibitor of caspase-1/interleukin-1β converting enzyme (ICE) and a non-acetylated form of Ac-YVAD-CHO. YVAD-CHO (trifluoroacetate salt) Chemical Structure
  28. GC45178 Z-DEVD-CMK (trifluoroacetate salt)

    Z-Asp-Glu-Val-Asp-CMK

    Z-DEVD-CMK is a protease inhibitor.

     Z-DEVD-CMK (trifluoroacetate salt) Chemical Structure
  29. GC40151 Z-VAD-AMC (acetate)

    Z-Val-Ala-Asp-AMC, Z-Val-Ala-Asp-7-amino-4-methylcoumarin

     Z-VAD-AMC is a fluorogenic substrate for caspase-1. Z-VAD-AMC (acetate) Chemical Structure
  30. GC40153 Z-YVAD-AFC (trifluoroacetate salt)

    Z-Tyr-Val-Ala-Asp-AFC, Z-Tyr-Val-Ala-Asp-7-amino-4-trifluoromethylcoumarin, Z-YVAD-7-amino-4-trifluoromethylcoumarin

     Z-YVAD-AFC is a fluorogenic substrate for caspase-1. Z-YVAD-AFC (trifluoroacetate salt) Chemical Structure
  31. GC45193 Z-YVAD-CMK (trifluoroacetate salt)

    Benxyloxycarbonyl-Tyr-Val-Ala-Asp-Chloromethylketone, Caspase-1 Inhibitor IV

    Z-YVAD-CMK is an inhibitor of caspase-1 and caspase-3.

     Z-YVAD-CMK (trifluoroacetate salt) Chemical Structure
  32. GC40119 Z-YVADLD-FMK (trifluoroacetate salt)

    Z-Tyr-Val-Ala-Asp-Leu-Asp-FMK

     Z-YVADLD-FMK is a peptide that contains the amino acid sequence YVAD, which is the cleavage site for caspase-1 and -4. Z-YVADLD-FMK (trifluoroacetate salt) Chemical Structure

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