Cholesterol Metabolism
Products for Cholesterol Metabolism
- Cat.No. 상품명 정보
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GC49690
(3R,5R)-Rosuvastatin (calcium salt)
A potential impurity found in bulk preparations of rosuvastatin
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GC40452
15(S)-HETE MaxSpec® Standard
15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway.
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GC40457
19(R)-HETE
19(R)-Hydroxyeicosatetraenoic Acid
19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II.
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GC40417
19-hydroxy Cholesterol
19-hydroxy Cholesterol is formed during metabolic oxidation of cholesterol.
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GC49671
2,3-Oxidosqualene
(3R,S)-Oxidosqualene, Squalene 2,3-oxide
An intermediate in the biosynthesis of sterols
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GC41614
24-dehydro Cholesterol
Desmosterol
24-디히드로콜레스테롤은 콜레스테롤과 유사한 분자입니다.
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GC46243
24-dehydro Cholesterol-d6
Desmosterol-d6
An internal standard for the quantification of 24-dehydro cholesterol
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GC46528
25-hydroxy Cholesterol-d6
An internal standard for the quantification of 25hydroxy cholesterol
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GC48449
28-(Poc-amino)betulin
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GC62033
3α-Hydroxy pravastatin sodium
3α-Isopravastatin, R-416
3α-하이드록시 프라바스타틴 나트륨은 프라바스타틴의 주요 대사 산물입니다.
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GC40799
3-hydroxy-3-Methylglutaric anhydride
Dicrotalic anhydride, HMG anhydride
The enzyme 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase mediates the rate-limiting step in cholesterol synthesis, converting HMG-CoA to mevalonate.
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GC42405
4-hydroxy Atorvastatin (calcium salt)
p-hydroxy Atorvastatin, para-hydroxy Atorvastatin
4-hydroxy Atorvastatin is a metabolite of atorvastatin, an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.
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GC18425
4-hydroxy Atorvastatin lactone
p-hydroxy Atorvastatin lactone, para-hydroxy Atorvastatin lactone
4-hydroxy Atorvastatin lactone is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.
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GC40535
6,15-diketo-13,14-dihydro Prostaglandin F1α
6,15diketo13,14dihydro PGF1α
6,15-diketo-13,14-dihydro PGF1α is a metabolite of PGI2.
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GC46889
Atorvastatin (calcium salt hydrate)
An HMG-CoA reductase inhibitor
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GC49421
Atorvastatin lactone-d5
An internal standard for the quantification of atorvastatin lactone
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GC46890
Atorvastatin-d5 (calcium salt)
An internal standard for the quantification of atorvastatin
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GC46911
Beauveriolide I
Beauveriolide I은 곤충병원성 진균 Beauveria sp.의 대사산물입니다.
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GC46912
Beauveriolide III
Beauveriolide III는 마우스 대식세포에서 지질 방울 형성의 억제제입니다.
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GC45390
Benazepril Acyl-β-D-Glucuronide
Benazapril Glucuronide
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GC19530
Brassicasterol
에르고스테롤(Ergosterol)의 대사산물인 브라시카스테롤(Brassicasterol)은 안드로겐 신호전달을 통한 방광 발암 촉진 억제 효과에 역할을 한다.
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GC43160
CAY10485
3,4dihydroxy Hydrocinnamic acid (LAspartic acid dibenzyl ester) amide
Acyl-coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis.
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GC40869
CAY10486
4Hydroxycinnamic acid (Lphenylalanine methyl ester) amide
Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis.
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GC47085
Cholesterol-d7
Provitamin D-d7
An internal standard for the quantification of cholesterol
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GC90700
Dendrogenin A
선택적 LXR 조절제 및 ChEH 억제제
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GC47367
Fluvastatin (sodium salt hydrate)
An HMG-CoA reductase inhibitor
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GC49303
Ganoderic Acid DM
Ganoderma lucidum에서 분리된 천연 트리테르페노이드인 Ganoderic acid DM은 인간 유방암 세포에서 DNA 손상, G1 세포 주기 정지 및 세포자멸사를 유도합니다.
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GC43745
Geranyl Pyrophosphate (triammonium salt)
GDP, Geranyl Diphosphate, GPP
제랄닐 파이로스포세이트 (트리아모늄 염)는 이소프레노이드 생합성 경로(IBP)에서 중요한 중간체입니다.
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GC45801
Hesperetin-13C-d3
A neuropeptide with diverse biological activities
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GC43883
Hymeglusin
Antibiotic 1233A
Hymeglusin은 곰팡이 β-lactone계 항생제로서 HMG-CoA synthase inhibitor이다(IC50=0.12μM).
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GC49486
Meglutol-d3
Dicrotalic Acid-d3, 3-hydroxy 3-methyl Glutaric Acid-d3, HMG-d3, 3-methyl-3-Hydroxyglutaric Acid-d3, Medroglutaric Acid-d3, 3-hydroxy-3-Methylglutaric Acid-d3
An internal standard for the quantification of meglutol
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GC48418
N-(2-Poc-ethyl)betulin amide
-
GC47756
N-desmethyl Rosuvastatin (sodium salt hydrate)
An active metabolite of rosuvastatin
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GC44497
Oleic Acid-2,6-diisopropylanilide
AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol.
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GC44590
Pellitorine
Pellitorine은 Piper nigrum의 뿌리에서 분리된 화합물입니다. Pellitorine은 HL60 및 MCT-7 세포주에 대해 강력한 세포독성 활성을 나타냅니다. Pellitorine은 암 질환 연구의 잠재력을 가지고 있습니다.
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GC49340
Pitavastatin lactone-d4
An internal standard for the quantification of pitavastatin lactone
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GC40220
Pravastatin-d3 (sodium salt)
프라바스타틴-d3(CS-514-d3) 나트륨염은 프라바스타틴 나트륨염으로 표지된 중수소입니다.
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GC49107
Rosuvastatin lactone
(+)-Rosuvastatin lactone, Rosuvastatin-5S-lactone, RSTL
The lactone form of rosuvastatin
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GC48060
Rosuvastatin-d6 (sodium salt)
An internal standard for the quantification of rosuvastatin
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GC49333
SH-42
DHCR24의 억제제
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GC50196
Simvastatin - d6
SVA-d6
Deuterated simvastatin
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GC45017
Terpendole C
Albophoma yamanashiensis가 생산하는 Terpendole C는 아실-CoA: 콜레스테롤 아실트랜스퍼라제(ACAT)에 대한 강력한 억제 활성을 나타냅니다.
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GC45060
TMP-153
Acyl-CoA:cholesterol acyltransferase (ACAT) catalyses the esterification of excess cellular cholesterol with fatty acids and is important for intestinal cholesterol absorption, hepatic lipoprotein secretion, and cholesterol accumulation in vascular tissues.
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GC45090
Triparanol
MER-29, NSC 65345
Triparanol is a 24-dehydro cholesterol reductase (DHCR24) inhibitor (Ki = 0.523 μM), which is an enzyme involved in the biosynthesis of cholesterol.