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홈 >> Signaling Pathways >> Neuroscience

Neuroscience

Neuroscience

Neuroscience

Neurons communicate with each other, effector organs and sensory organs through the neurotransmitter – receptor pathway at synapses. Neurotransmitters can be divided into 4 major groups: 1. Amino acids (glumate, aspartate, serine, glycine and GABA); 2. Monoamines (norepinephrine, epinephrine, dopamine, histamine, and serotonin); 3. Peptides (opioid peptides, substance P, somatostatin); and 4. Others (acetylcholine, NO, nucleosides).

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Products for  Neuroscience

  1. Cat.No. 상품명 정보
  2. GC32655 5-HT2 antagonist 1 5-HT2 길항제 1은 5-HT2 수용체의 강력한 길항제로, 약한 α1 아드레날린 수용체 차단 활성을 갖는다. 5-HT2 antagonist 1 Chemical Structure
  3. GC32664 5-HT2A antagonist 1 5-HT2A 길항제 1은 특허 US5728835A 및 JP 1007727에서 추출한 5-HT2A 길항제입니다. 5-HT2A antagonist 1 Chemical Structure
  4. GC65568 5-HT2B antagonist-1 5-HT2B 길항제-1은 33.4 nM의 IC50 값을 갖는 경구 활성 5-HT2B 수용체 길항제입니다. 5-HT2B antagonist-1 Chemical Structure
  5. GC31263 5-HT3 antagonist 1 5-HT3 길항제 1은 세로토닌 3(5-HT3) 수용체의 강력하고 선택적인 길항제입니다. 5-HT3 antagonist 1 Chemical Structure
  6. GC31247 5-HT3 antagonist 2 5-HT3 길항제 2는 5-HT3 수용체 길항제입니다. 5-HT3 antagonist 2 Chemical Structure
  7. GC65983 5-HT3 antagonist 5 5-HT3 길항제 5는 5-HT3 수용체 길항제인 퀴녹살린-2-카르복스아미드 화합물입니다. 821d96072c2d58d8970e76f526b0f6b85-HT3 길항제 5는 5-HT3 작용제 및 2-메틸-5-HT에 대해 길항 작용을 하며 마우스에서 항우울 효과를 나타낸다.821d96072c2d58d8970e76f526b0f6b8 5-HT3 antagonist 5 Chemical Structure
  8. GC31227 5-HT3-In-1 5-HT3-In-1은 특허 EP0748807A1, 화합물 실시예 8에서 추출됩니다. 5-HT3-In-1 Chemical Structure
  9. GC30314 5-HT4 antagonist 1 5-HT4 길항제 1은 pKi가 9.6인 5-HT4 수용체 길항제입니다. 5-HT4 antagonist 1 Chemical Structure
  10. GC31144 5-HT7 agonist 1 5-HT7 작용제 1은 IC50이 222.93nM인 선택적 5-HT7 수용체 작용제이며 CNS 장애와 같은 5-HT7 수용체 관련 질병에 사용할 수 있습니다. 5-HT7 agonist 1 Chemical Structure
  11. GC49655 5-hydroxy Buspirone A metabolite of buspirone 5-hydroxy Buspirone Chemical Structure
  12. GC49119 5-hydroxy Flunixin A metabolite of flunixin 5-hydroxy Flunixin Chemical Structure
  13. GC52172 5-hydroxy Indole-3-acetic Acid-d6 5-hydroxy Indole-3-acetic Acid-d6 Chemical Structure
  14. GC49315 5-hydroxy Indomethacin A metabolite of indomethacin 5-hydroxy Indomethacin Chemical Structure
  15. GC52106 5-hydroxy Isatin An inhibitor of MAO-A 5-hydroxy Isatin Chemical Structure
  16. GC42550 5-hydroxy-6-methoxy (S)-Duloxetine 5-hydroxy-6-methoxy (S)-Duloxetine is a metabolite of (S)-duloxetine. 5-hydroxy-6-methoxy (S)-Duloxetine Chemical Structure
  17. GC42553 5-hydroxy-Nω-methyl Tryptamine (oxalate)

    5-hydroxy-Nω-methyl Tryptamine is a metabolite of serotonin in humans that has also been found in plants.

     5-hydroxy-Nω-methyl Tryptamine (oxalate) Chemical Structure
  18. GC11626 5-Iodo-A-85380 dihydrochloride α4β2 and α6β2 nicotinic acetylcholine receptors agonist 5-Iodo-A-85380 dihydrochloride Chemical Structure
  19. GC14225 5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative Precursor to ligand for the α4β2 nicotinic receptor 5-Iodo-A-85380, 5-trimethylstannyl N-BOC derivative Chemical Structure
  20. GC14940 5-Methoxytryptamine 5-Methoxytryptamine Chemical Structure
  21. GC64182 5-Methoxytryptamine hydrochloride 5-Methoxytryptamine hydrochloride Chemical Structure
  22. GC14604 5-Methylfurmethiodide muscarinic agonist 5-Methylfurmethiodide Chemical Structure
  23. GC46706 5-Methyltetrahydrofolic Acid (hydrate) A biologically active form of folic acid 5-Methyltetrahydrofolic Acid (hydrate) Chemical Structure
  24. GC17477 5-Nonyloxytryptamine oxalate 5-HT1B agonist 5-Nonyloxytryptamine oxalate Chemical Structure
  25. GC41156 5-Octyl D-glutamate 5-Octyl D-glutamate, also known as 5-octyl ester D-glutamate, is a stable, cell-permeable molecule that generates free D-glutamate upon hydrolysis of the ester bond by cytoplasmic esterases. 5-Octyl D-glutamate Chemical Structure
  26. GC41094 5-trans Latanoprost Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. 5-trans Latanoprost Chemical Structure
  27. GC41228 5-trans Latanoprost (free acid) Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. 5-trans Latanoprost (free acid) Chemical Structure
  28. GC49438 5-trans-17-phenyl trinor Prostaglandin F2α The 5-trans isomer of 17-phenyl trinor PGF2α 5-trans-17-phenyl trinor Prostaglandin F2α Chemical Structure
  29. GC31296 5HT6-ligand-1 5HT6-리간드-1은 1.43nM의 Ki를 갖는 강력한 5-HT6 수용체 리간드입니다. 5HT6-ligand-1 Chemical Structure
  30. GC18176 5α,6β-Dihydroxycholestanol 5α,6β-Dihydroxycholestanol is an oxysterol metabolite of cholesterol formed from conversion of cholesterol epoxides by 5,6-epoxysterol hydrolase. 5α,6β-Dihydroxycholestanol Chemical Structure
  31. GC30943 6,2'-Dihydroxyflavone 6,2'-Dihydroxyflavone은 GABAA 수용체의 새로운 길항제입니다. 6,2'-Dihydroxyflavone Chemical Structure
  32. GC46720 6,9-Dichloro-1,2,3,4-tetrahydroacridine A synthetic intermediate in the synthesis of AChE inhibitors 6,9-Dichloro-1,2,3,4-tetrahydroacridine Chemical Structure
  33. GC11284 6-(4-Methoxyphenyl)-3-pyridazinamine GABAA receptor antagonist 6-(4-Methoxyphenyl)-3-pyridazinamine Chemical Structure
  34. GC42572 6-Amino-8-trifluoromethylphenanthridine 6-Amino-8-trifluoromethylphenanthridine (6A-8tFP) is an antiprion agent and a derivative of 6-aminophenanthridine. 6-Amino-8-trifluoromethylphenanthridine Chemical Structure
  35. GC40479 6-Aminophenanthridine 6-아미노페난트리딘은 리보솜(PFAR)의 단백질 접힘 활성을 억제합니다. 6-Aminophenanthridine Chemical Structure
  36. GC14000 6-fluoro-DL-Tryptophan 6-플루오로-DL-트립토판은 트립토판 수산화효소의 강력하고 경쟁적인 억제제입니다. 6-fluoro-DL-Tryptophan Chemical Structure
  37. GC42580 6-hydroxy Chlorzoxazone

    6-hydroxy Chlorzoxazone is a metabolite of chlorzoxazone.

     6-hydroxy Chlorzoxazone Chemical Structure
  38. GC49183 6-hydroxy Etodolac A metabolite of etodolac 6-hydroxy Etodolac Chemical Structure
  39. GC16267 6-Hydroxydopamine hydrobromide

    옥시도파민(6-OHDA) 하이드로브로마이드는 신경전달물질 도파민의 상대작용제입니다.

     6-Hydroxydopamine hydrobromide Chemical Structure
  40. GC16153 6-methoxy Naphthalene Acetic Acid competitive, non-selective COX inhibitor 6-methoxy Naphthalene Acetic Acid Chemical Structure
  41. GC31309 6-Methoxy-2-naphthoic acid (Naproxen impurity O) 6-메톡시-2-나프토산(나프록센 불순물 O)은 특허 WO 2012019106 A2에서 추출된 NMDA 수용체 조절제입니다. 6-Methoxy-2-naphthoic acid (Naproxen impurity O) Chemical Structure
  42. GC30898 6-Methylflavone 6-Methylflavone은 α1β2γ2L 및 α1β2 GABAA 수용체의 활성화제입니다. 6-Methylflavone Chemical Structure
  43. GC42584 6-O-desmethyl Donepezil 6-O-desmethyl Donepezil is an active metabolite of the acetylcholinesterase inhibitor donepezil. 6-O-desmethyl Donepezil Chemical Structure
  44. GC10781 7-Chlorokynurenic acid 7-클로로키누렌산(7-CKA)은 N-메틸-D-아스파테이트(NMDA) 수용체(IC50=0.56μM)의 글리신 B 공작용제 부위의 강력하고 선택적인 길항제입니다. 7-Chlorokynurenic acid Chemical Structure
  45. GC11395 7-Chlorokynurenic acid sodium salt 7-클로로키누렌산 나트륨염(7-CKA 나트륨염)은 N-메틸-D-아스파테이트(NMDA) 수용체(IC50=0.56μM)의 글리신 B 공작용제 부위의 강력하고 선택적인 길항제입니다. 7-Chlorokynurenic acid sodium salt Chemical Structure
  46. GC46242 7-dehydro Cholesterol-d7

    7-dehydro Cholesterol (7-DHC) is an immediate precursor of cholesterol

     7-dehydro Cholesterol-d7 Chemical Structure
  47. GC48649 7-hydroxy Chlorpromazine (hydrochloride) An active metabolite of chlorpromazine 7-hydroxy Chlorpromazine (hydrochloride) Chemical Structure
  48. GC35192 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone 7-하이드록시-3,4-디하이드로-2(1H)-퀴놀리논(3,4-디하이드로-7-하이드록시-2(1H)-퀴놀리논)은 약한 MAO-A 억제제이며, IC50은 183μM이며 MAO-B에 영향을 미치지 않습니다. 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone Chemical Structure
  49. GC16574 7-Hydroxy-DPAT hydrobromide D3 dopamine receptor agonist 7-Hydroxy-DPAT hydrobromide Chemical Structure
  50. GC40572 7-keto Cholesterol 독성 옥시스테롤인 7-케토 콜레스테롤은 담즙산 생합성 콜레스테롤 7 알파-하이드록실라제의 속도 제한 단계를 억제할 뿐만 아니라 HMG-CoA 환원효소(콜레스테롤 생합성의 속도 제한 효소)를 강력하게 억제합니다. 7-keto Cholesterol Chemical Structure
  51. GC46241 7-keto Cholesterol-d7

    7-keto Cholesterol is a bioactive sterol and a major oxysterol component of oxidized LDL

     7-keto Cholesterol-d7 Chemical Structure
  52. GC48880 7-Methoxyflavone 7-Methoxyflavone은 Zornia brasiliensis에서 분리된 화합물입니다. 7-Methoxyflavone Chemical Structure
  53. GC15338 8,11,14-Eicosatriynoic Acid A Cox, 12-LO, and 5-LO inhibitor 8,11,14-Eicosatriynoic Acid Chemical Structure
  54. GC40587 8,12-iso-iPF2α-VI 8,12-iso-iPF2α-VI is an isoprostane produced by non-enzymatic, free radical-induced peroxidative damage to membrane lipids. 8,12-iso-iPF2α-VI Chemical Structure
  55. GC49017 8-hydroxy Amoxapine A metabolite of amoxapine 8-hydroxy Amoxapine Chemical Structure
  56. GC42626 8-hydroxy Efavirenz 8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz. 8-hydroxy Efavirenz Chemical Structure
  57. GC18654 8-hydroxy Loxapine 8-hydroxy Loxapine (8-OH loxapine) is a metabolite formed when loxapine , an atypical antipsychotic, is metabolized by the cytochrome P450 isoform CYP1A2. 8-hydroxy Loxapine Chemical Structure
  58. GC49544 8-hydroxy Mirtazapine A metabolite of mirtazapine 8-hydroxy Mirtazapine Chemical Structure
  59. GC14966 8-Hydroxy-DPAT hydrobromide 8-하이드록시-DPAT 하이드로브로마이드(8-OH-DPAT 하이드로브로마이드)는 pIC50이 8.19인 강력하고 선택적인 5-HT1A 작용제입니다. 8-Hydroxy-DPAT hydrobromide Chemical Structure
  60. GC12427 8-Hydroxy-PIPAT oxalate 5-HT1A receptor agonist 8-Hydroxy-PIPAT oxalate Chemical Structure
  61. GC40759 8-methyl Nonanoic Acid

    Capsaicin, the chemical that imparts the spicy-hot quality of chili peppers, is produced by the fruits of plants belonging to the Capsicum family.

     8-methyl Nonanoic Acid Chemical Structure
  62. GC30888 8-OH-DPAT (8-Hydroxy-DPAT) 8-OH-DPAT(8-Hydroxy-DPAT)는 강력하고 선택적인 5-HT 작용제로서 5-HT1A의 경우 pIC50이 8.19이고 5-HT7의 경우 Ki가 466nM입니다. 8-OH-DPAT(8-Hydroxy-DPAT)는 5-HT1B(pIC50, 5.42), 5-HT(pIC50 <5)에 약하게 결합합니다. 8-OH-DPAT (8-Hydroxy-DPAT) Chemical Structure
  63. GC46753 9(S),12(S),13(S)-TriHOME An oxylipin 9(S),12(S),13(S)-TriHOME Chemical Structure
  64. GC42640 9(Z),12(Z),15(Z),18(Z),21(Z)-Tetracosapentaenoic Acid 9(Z),12(Z),15(Z),18(Z),21(Z)-Tetracosapentaenoic acid is an ω-3 very long-chain polyunsaturated fatty acid. 9(Z),12(Z),15(Z),18(Z),21(Z)-Tetracosapentaenoic Acid Chemical Structure
  65. GC14302 9,12-Octadecadiynoic Acid 9,12-Octadecadiynoic Acid(9a,12a-Octadecadiynoic acid)는 식물 리폭시게나제 억제제입니다. 9,12-Octadecadiynoic Acid Chemical Structure
  66. GC13537 A 331440 dihydrochloride H3 receptor antagonist,non-imidazole,high affinity A 331440 dihydrochloride Chemical Structure
  67. GC14610 A 412997 dihydrochloride Selective D4 agonist A 412997 dihydrochloride Chemical Structure
  68. GC12739 A 484954 A 484954는 IC50이 280nM인 고도로 선택적인 eEF2(진핵 신장 인자-2) 억제제입니다. A 484954 Chemical Structure
  69. GC17805 A 582941 A 582941은 α7 nAChR의 강력하고 선택적인 뇌 침투 부분 작용제이며, 쥐의 뇌막과 인간의 전두엽에서 Kis는 각각 10.8과 16.7nM입니다. A 582941 Chemical Structure
  70. GC15498 A 68930 hydrochloride 68930 염산염은 도파민 D1 수용체 작용제로 기관지 확장증 연구에 사용할 수 있습니다. A 68930 hydrochloride Chemical Structure
  71. GC11183 A 77636 hydrochloride A 77636 염산염은 항파킨슨병 활성이 있는 강력한 경구 활성, 선택적 및 장기 작용 도파민 D1 수용체 작용제(pKi\u003d7.40; Ki\u003d39.8 nM)입니다. A 77636 hydrochloride Chemical Structure
  72. GC15434 A 839977 839977은 P2X7 선택적 길항제입니다. 재조합 인간, 쥐 및 마우스 P2X7 수용체(IC50 값은 각각 20nM, 42nM 및 150nM)에서 BzATP 유발 칼슘 유입을 차단하고 동물 모델에서 염증성 및 신경병성 통증을 감소시킵니다. P2X7 수용체 차단의 항통각과민 효과는 IL-1베타의 방출을 차단함으로써 매개됩니다. A 839977 Chemical Structure
  73. GC16068 A 841720 A 841720은 인간 mGlu1 수용체에 대한 IC50이 10nM인 강력하고 비경쟁적이며 선택적인 mGlu1 수용체 길항제입니다. A 841720 Chemical Structure
  74. GC15333 A 844606 α7 nAChR partial agonist A 844606 Chemical Structure
  75. GC11121 A 943931 dihydrochloride Antagonist of histamine H4 receptor,potent and selective A 943931 dihydrochloride Chemical Structure
  76. GC17743 A 987306 A 987306은 강력한 경구 생체이용성 히스타민 H4 길항제이며, Kis는 랫트 H4 및 인간 H4에 대해 3.4nM 및 5.8nM입니다. A 987306 Chemical Structure
  77. GC63502 Aβ/tau aggregation-IN-1 Aβ/타우 응집-IN-1은 강력한 Aβ1-42 β-시트 형성 및 타우 응집 억제제입니다. Aβ/tau aggregation-IN-1 Chemical Structure
  78. GC60037 A-3 hydrochloride A-3 염산염은 다양한 키나제의 강력한 세포 투과성, 가역성, ATP 경쟁적 비선택적 길항제입니다. A-3 hydrochloride Chemical Structure
  79. GC19499 A-381393 A-381393은 인간 도파민 D4.4, D4.2 및 D4.7 수용체에 대해 각각 1.5, 1.9 및 1.6 nM의 Kis를 갖는 강력하고 선택적인 뇌 침투 도파민 D4 수용체 길항제이며 D1, D2, D3 및 D5 도파민 수용체. A-381393 Chemical Structure
  80. GC31214 A-437203 (Lu201640) A-437203(Lu201640)은 D2, D3 및 D4 수용체에 대해 Ki가 각각 71, 1.6 및 6220nM인 선택적 D3 수용체 길항제입니다. A-437203 (Lu201640) Chemical Structure
  81. GC11842 A-740003 A selective P2X7 antagonist A-740003 Chemical Structure
  82. GC15014 A-867744 A positive allosteric modulator of α7 nAChRs A-867744 Chemical Structure
  83. GC10641 AA 29504 GABAA receptor modulator AA 29504 Chemical Structure
  84. GC31055 Abaperidone 아바페리돈은 6.2 및 17 nM의 IC50을 갖는 5-HT2A 수용체 및 도파민 D2 수용체의 강력한 길항제입니다. Abaperidone Chemical Structure
  85. GC42674 ABD459 ABD459 is a neutral antagonist of the central cannabinoid 1 (CB1) receptor (Ki = 8.6 nM). ABD459 Chemical Structure
  86. GC11795 ABT 724 trihydrochloride ABT 724 삼염산염은 인간 도파민 D4 수용체에 대한 EC50이 12.4nM인 강력하고 고도로 선택적인 도파민 D4 수용체 작용제입니다. ABT 724 trihydrochloride Chemical Structure
  87. GC35222 ABT-239 ABT-239는 새롭고 매우 효과적인 비이미다졸 계열의 H3R 길항제이자 일과성 수용체 전위 바닐로이드 1형(TRPV1) 길항제입니다. ABT-239 Chemical Structure
  88. GC33552 ABT-670 ABT-670은 인간 D4, 흰 족제비 D4 및 쥐 D4에 대해 EC50이 각각 89nM, 160nM 및 93nM인 도파민 D4 수용체의 선택적 경구 생체 이용 가능 작용제입니다. ABT-670 Chemical Structure
  89. GP10121 Ac-Endothelin-1 (16-21), human Ac-Endothelin-1 (16-21), human Chemical Structure
  90. GC42721 Ac-YVAD-CMK

    Ac-YVAD-CMK는 카스패이스-1의 선택적인 불가역 억제제입니다(Ki=0.8nM). 이것은 염증 유발 사이토카인 IL-1β 활성화를 방지할 수 있습니다. Ac-YVAD-CMK는 염증 반응을 감소시키고 장기간 신경 보호 효과를 유도할 수 있습니다.

     Ac-YVAD-CMK Chemical Structure
  91. GC49263 Ac2-26 (human) (ammonium salt) An annexin A1-mimetic peptide Ac2-26 (human) (ammonium salt) Chemical Structure
  92. GC30859 AC260584 AC260584는 pEC50이 7.6인 M1 무스카린 수용체 알로스테릭 작용제입니다. AC260584 Chemical Structure
  93. GC14916 Acamprosate calcium An NMDA modulator Acamprosate calcium Chemical Structure
  94. GC46778 Acamprosate-d3 (calcium salt) An internal standard for the quantification of acamprosate Acamprosate-d3 (calcium salt) Chemical Structure
  95. GC17079 ACDPP hydrochloride mGlu5 receptor antagonist ACDPP hydrochloride Chemical Structure
  96. GC64332 Aceclidine 아세클리딘은 M3 무스카린성 아세틸콜린 수용체의 조절제입니다. Aceclidine Chemical Structure
  97. GC12787 Aceclidine (hydrochloride) agonist of muscarinic receptors Aceclidine (hydrochloride) Chemical Structure
  98. GC15902 Aceclofenac Aceclofenac은 진통 및 항염증 특성이 있는 경구 활성 비스테로이드성 항염증제(NSAID)입니다. Aceclofenac Chemical Structure
  99. GC42691 Aceclofenac ethyl ester A potential impurity found in commercial preparations of aceclofenac Aceclofenac ethyl ester Chemical Structure
  100. GC42692 Aceclofenac methyl ester A potential impurity in commercial preparations of aceclofenac Aceclofenac methyl ester Chemical Structure
  101. GC10454 Acemetacin 아세메타신(TVX 1322)은 비스테로이드성 소염제이자 시클로옥시게나제 억제제인 인도메타신의 글리콜산 에스테르입니다. Acemetacin Chemical Structure

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