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홈 >> Signaling Pathways >> Cell Cycle/Checkpoint >> Cytoskeleton & Motor Proteins

Cytoskeleton & Motor Proteins

Products for  Cytoskeleton & Motor Proteins

  1. Cat.No. 상품명 정보
  2. GC41268 (E)-2-Hexadecenal Sphingosine-1-phosphate (S1P), a bioactive lipid involved in many signaling processes, is irreversibly degraded by the membrane-bound S1P lyase. (E)-2-Hexadecenal Chemical Structure
  3. GC41701 (E)-2-Hexadecenal Alkyne (E)-2-Hexadecenal alkyne is an alkyne version of the sphingolipid degradation product (E)-2-hexadecenal that can be used as a click chemistry probe. (E)-2-Hexadecenal Alkyne Chemical Structure
  4. GC41719 (R)-nitro-Blebbistatin (R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin, which is the inactive form of (-)-blebbistatin. (R)-nitro-Blebbistatin Chemical Structure
  5. GC41557 (S)-3'-amino Blebbistatin (S)-3'-amino Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-3'-amino Blebbistatin Chemical Structure
  6. GC41484 (S)-3'-hydroxy Blebbistatin (S)-3'-hydroxy Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-3'-hydroxy Blebbistatin Chemical Structure
  7. GC52192 (S)-4'-nitro-Blebbistatin (S)-4'-nitro-Blebbistatin은 생리학적, 발달 및 세포 생물학 연구에서 미오신 II의 특정 역할에 대한 연구에 사용되는 비세포독성, 광안정성, 형광성 및 특정 미오신 II 억제제입니다. (S)-4'-nitro-Blebbistatin Chemical Structure
  8. GC41739 (S)-nitro-Blebbistatin (S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-nitro-Blebbistatin Chemical Structure
  9. GC49736 10-acetyl Docetaxel 10-아세틸 도세탁셀(10-Acetyl docetaxel)은 항암 활성이 있는 도세탁셀의 유사체입니다. 도세탁셀은 유사분열 억제 활성이 있는 미세소관 분해 억제제입니다. 10-acetyl Docetaxel Chemical Structure
  10. GC41110 16-epi Latrunculin B 16-epi Latrunculin B, first isolated from the Red Sea sponge N. 16-epi Latrunculin B Chemical Structure
  11. GC48423 19-O-Acetylchaetoglobosin A 19-O-Acetylchaetoglobosin A는 cytochalasan alkaloid로 C. globosum에서 원래 분리된 곰팡이 대사산물로 액틴 중합 억제 및 세포 독성 활성을 가지고 있습니다. 19-O-아세틸키토글로보신 A는 HeLa 자궁경부암 세포에 세포독성을 나타냅니다. 19-O-Acetylchaetoglobosin A Chemical Structure
  12. GC52029 2-Aminoflubendazole 2-아미노플루벤다졸은 벤지미다졸의 대사산물입니다. 2-Aminoflubendazole Chemical Structure
  13. GC49244 4-oxo Isotretinoin An active metabolite of isotretinoin 4-oxo Isotretinoin Chemical Structure
  14. GC48721 6-O-Demethyl Griseofulvin A metabolite of griseofulvin 6-O-Demethyl Griseofulvin Chemical Structure
  15. GC40844 9-(2,2-Dicyanovinyl)julolidine 9-(2,2-Dicyanovinyl)julolidine(9-(2,2-Dicyanovinyl)julolidine)은 분자 회전자이자 독특한 형광 염료로 tubulin과 actin에 결합하여 중합 시 형광 강도를 급격히 증가시킵니다. 9-(2,2-Dicyanovinyl)julolidine Chemical Structure
  16. GC25025 Abraxane Abraxane (Nab-Paclitaxel), a novel solvent-free taxane with the binding ratio of Paclitaxel to human serum albumin of 1:9, is an anti-microtubule drug that promotes microtubule aggregation in tubulin dimer and inhibits microtubule depolymerization to stabilize the microtubule system. Abraxane Chemical Structure
  17. GC18274 Amiprofos-methyl 아미프로포스-메틸(BAY-NTN 6867)은 인산 아미드 제초제입니다. Amiprofos-methyl Chemical Structure
  18. GC25075 Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222) Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222, Antibiotic C 15003P3) is a potent inhibitor of tubulin polymerization with IC50 of 3.4 μM. Ansamitocin p-3 (Maytansinol isobutyrate, NSC292222) Chemical Structure
  19. GC42933 Binucleine 2 Binucleine 2 is an isoform-specific and ATP-competitive inhibitor of Drosophila Aurora B kinase (Ki = 0.36 μM), a kinase involved in cell division. Binucleine 2 Chemical Structure
  20. GC18408 BML-278 BML-278 is an activator of sirtuin 1 (SIRT1) that has an EC150 value (effective concentration able to increase the enzyme by 150%) of 1 uM. BML-278 Chemical Structure
  21. GC46946 BPC 157 (acetate) A pentadecapeptide with diverse biological activities BPC 157 (acetate) Chemical Structure
  22. GC45395 Cabazitaxel-d9 카바지탁셀-d9는 카바지탁셀로 표지된 중수소입니다. 카바지탁셀은 잠재적인 항종양 활성을 가진 천연 탁소이드 10-데아세틸바카틴 III의 반합성 유도체입니다. Cabazitaxel-d9 Chemical Structure
  23. GC43135 Cambendazol Cambendazol은 인간 강경화증의 치료에 가장 효과적인 약제 중 하나이며 . Cambendazol Chemical Structure
  24. GC40890 CAY10701 CAY10701 is a 7-deazahypoxanthine analog that prevents microtubule formation, blocking the proliferation of HeLa and MCF-7 cells (GI50s = 22 and 38 nM, respectively). CAY10701 Chemical Structure
  25. GC52367 Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide A biotinylated and citrullinated mutant vimentin peptide Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide Chemical Structure
  26. GC52370 Citrullinated Vimentin (R144) (139-159)-biotin Peptide A biotinylated and citrullinated vimentin peptide Citrullinated Vimentin (R144) (139-159)-biotin Peptide Chemical Structure
  27. GC40664 Colcemid

    콜세미드는 포유류 세포나 난자에서 각각 G2/M 단계의 유사분열 정지 또는 소포 파열(GVBD) 단계의 준비 분열 정지를 유도하는 세포골격 억제제입니다.

     Colcemid Chemical Structure
  28. GC47117 Colchicine-d6 콜히친-d6은 콜히친이라는 라벨이 붙은 중수소입니다. 콜히친은 튜불린 억제제이자 미세소관 교란제입니다. 콜히친은 3 nM의 IC50으로 미세소관 중합을 억제합니다. 콜히친은 또한 α3 글리신 수용체(GlyR)의 경쟁적 길항제입니다. Colchicine-d6 Chemical Structure
  29. GC49913 Davunetide (acetate) A neuroprotective ADNP-derived peptide Davunetide (acetate) Chemical Structure
  30. GC43469 Diminutol Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. Diminutol Chemical Structure
  31. GC48968 Docetaxel (hydrate)

    An analog of taxol with antitumor properties

     Docetaxel (hydrate) Chemical Structure
  32. GC47250 Docetaxel-d9 도세탁셀-d9(RP-56976-d9)는 도세탁셀로 표시된 중수소입니다. Docetaxel(RP-56976)은 IC50이 0.2μM인 미세소관 해중합 억제제입니다. 도세탁셀은 bcl-2 및 bcl-xL 유전자 발현의 효과를 약화시킵니다. Docetaxel은 G2/M에서 세포 주기를 정지시키고 세포 사멸을 유도합니다. 도세탁셀은 항암 활성이 있습니다. Docetaxel-d9 Chemical Structure
  33. GC49124 EN219 EN219는 470nM의 IC50을 갖는 RNF114의 N-말단 시스테인(C8)에 대한 적당히 선택적인 합성 공유 리간드입니다. EN219는 RNF114 매개 자가유비퀴틴화 및 p21 유비퀴틴화를 억제합니다. EN219 Chemical Structure
  34. GC48720 Griseofulvic Acid A metabolite of griseofulvin Griseofulvic Acid Chemical Structure
  35. GC48688 Griseofulvin-d3 An internal standard for the quantification of griseofulvin Griseofulvin-d3 Chemical Structure
  36. GC40048 MPS1/TTK Inhibitor MPS1/TTK inhibitor is an inhibitor of monopolar spindle 1 (MPS1/TTK; IC50 = 5.8 nM), a kinase involved in mitotic spindle checkpoint signaling that is overexpressed in certain cancerous tumors. MPS1/TTK Inhibitor Chemical Structure
  37. GC41564 MPT0B014 An inhibitor of tubulin polymerization MPT0B014 Chemical Structure
  38. GC18445 N-Deacetylcolchicine An inhibitor of microtubule polymerization N-Deacetylcolchicine Chemical Structure
  39. GC49404 Paclitaxel C A taxoid and an inhibitor of microtubule depolymerization Paclitaxel C Chemical Structure
  40. GC45944 para-amino-Blebbistatin

    향상된 수용성을 가진 덜 광독성의 (–)-블레비스타틴의 안정적인 형태

     para-amino-Blebbistatin Chemical Structure
  41. GC44618 Phalloidin-AMCA Conjugate Phalloidin-AMCA conjugate is a blue fluorophore that specifically labels filamentous actin (F-actin). Phalloidin-AMCA Conjugate Chemical Structure
  42. GC44620 Phalloidin-Tetramethylrhodamine Conjugate Phalloidin-retramethylrhodamine conjugate is an orange fluorescent probe (ex/em = 546/575 nm) that selectively binds to F-actin. Phalloidin-Tetramethylrhodamine Conjugate Chemical Structure
  43. GC48394 Phomopsinamine An inhibitor of microtubule polymerization Phomopsinamine Chemical Structure
  44. GC49077 Podophyllotoxin-d6 An internal standard for the quantification of podophyllotoxin and picropodophyllotoxin Podophyllotoxin-d6 Chemical Structure
  45. GC44800 Quininib A CysLT1 and CysLT2 receptor antagonist Quininib Chemical Structure
  46. GC45688 STX140 An estrogen sulfamate STX140 Chemical Structure
  47. GC48119 Suprafenacine An inhibitor of tubulin polymerization with anticancer activity Suprafenacine Chemical Structure
  48. GC44976 Swinholide A Swinholide A는 액틴 결합 해양 폴리케타이드이며 ~ 50nM의 Kd로 액틴을 이량체화합니다. Swinholide A Chemical Structure
  49. GC45750 Thymosin β4 (human, mouse, rat, porcine, bovine) (acetate) An actin-sequestering peptide Thymosin β4 (human, mouse, rat, porcine, bovine) (acetate) Chemical Structure
  50. GC18763 TN-16 TN-16은 IC50이 0.4-1.7 μM인 미세소관 중합의 강력한 억제제입니다. TN-16 Chemical Structure
  51. GC52364 Vimentin (139-159)-biotin Peptide A biotinylated vimentin peptide Vimentin (139-159)-biotin Peptide Chemical Structure
  52. GC52371 Vimentin (G146R) (139-159)-biotin Peptide A biotinylated mutant vimentin peptide Vimentin (G146R) (139-159)-biotin Peptide Chemical Structure
  53. GC45595 Vulpinic Acid 이끼 대사산물인 Vulpinic acid는 H2O2로 인한 ROS 생성, 산화 스트레스 및 인간 제대 정맥 내피 세포(HUVEC)의 산화 스트레스 관련 손상을 감소시킵니다. Vulpinic Acid Chemical Structure
  54. GC18578 YK-3-237 SIRT1 활성화제인 YK-3-237은 돌연변이 p53을 표적으로 합니다. YK-3-237은 삼중음성 유방암 세포의 증식을 억제합니다. YK-3-237 Chemical Structure

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