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홈 >> Signaling Pathways >> Immunology/Inflammation >> Autoimmunity

Autoimmunity

Products for  Autoimmunity

  1. Cat.No. 상품명 정보
  2. GC52253 α-Enolase (1-19)-biotin Peptide A biotinylated α-enolase peptide α-Enolase (1-19)-biotin Peptide Chemical Structure
  3. GC48292 α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) α-MSH(⋱-멜라닌 세포 자극 호르몬) TFA는 내인성 신경 펩티드이며 항염 및 해열 활성을 갖는 내인성 멜라노코르틴 수용체 4(MC4R) 작용제입니다. α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) Chemical Structure
  4. GC40467 (±)11-HETE (±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. (±)11-HETE Chemical Structure
  5. GC45263 (+)-D-threo-PDMP (hydrochloride) (+)-D-threo-PDMP is a ceramide analog and is one of the four possible stereoisomers of PDMP. (+)-D-threo-PDMP (hydrochloride) Chemical Structure
  6. GC52185 (R,S)-Anatabine-d4 (R,S)-Anatabine-d4 Chemical Structure
  7. GC49759 13C17-Mycophenolic Acid An internal standard for the quantification of mycophenolic acid 13C17-Mycophenolic Acid Chemical Structure
  8. GC49912 13C20,15N10-Cyclic di-GMP (sodium salt) An internal standard for the quantification of cyclic di-GMP 13C20,15N10-Cyclic di-GMP (sodium salt) Chemical Structure
  9. GC41950 16α-hydroxy Estrone 16α-하이드록시 에스트론(16αOHE)은 주요 에스트라디올 대사 산물입니다. 16α-hydroxy Estrone Chemical Structure
  10. GC42080 2'2'-cGAMP (sodium salt) 2'2'-cGAMP is a synthetic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds. 2'2'-cGAMP (sodium salt) Chemical Structure
  11. GC40960 20α-dihydro Prednisolone 20α-dihydro Prednisolone is a metabolite of prednisolone. 20α-dihydro Prednisolone Chemical Structure
  12. GC18527 4'-hydroxy Flurbiprofen A major active metabolite of flurbiprofen 4'-hydroxy Flurbiprofen Chemical Structure
  13. GC49127 4-oxo Cyclophosphamide An inactive metabolite of cyclophosphamide 4-oxo Cyclophosphamide Chemical Structure
  14. GC18582 5'-hydroxy Meloxicam A metabolite of meloxicam 5'-hydroxy Meloxicam Chemical Structure
  15. GC48381 5'-pApA (sodium salt) A linearized form of cyclic di-AMP 5'-pApA (sodium salt) Chemical Structure
  16. GC48375 5'-pGpG (sodium salt) A linearized form of cyclic di-GMP 5'-pGpG (sodium salt) Chemical Structure
  17. GC52413 5-Aminosalicylic Acid-d7 An internal standard for the quantification of 5-aminosalicylic acid 5-Aminosalicylic Acid-d7 Chemical Structure
  18. GC49629 6β-hydroxy Prednisolone A metabolite of prednisolone 6β-hydroxy Prednisolone Chemical Structure
  19. GC45772 6(5H)-Phenanthridinone An inhibitor of PARP1 and 2 6(5H)-Phenanthridinone Chemical Structure
  20. GC49235 6-Methylmercaptopurine A metabolite of 6-mercaptopurine 6-Methylmercaptopurine Chemical Structure
  21. GC49488 6-Methylmercaptopurine-d3 An internal standard for the quantification of 6-MMP 6-Methylmercaptopurine-d3 Chemical Structure
  22. GC49051 7-hydroxy Methotrexate 7-하이드록시 메토트렉세이트는 메토트렉세이트의 주요 대사 산물입니다. 7-hydroxy Methotrexate Chemical Structure
  23. GC42608 7-hydroxy Methotrexate (sodium salt)

    7-hydroxy Methotrexate (7-hydroxy MTX) is a phase I metabolite of MTX, which is converted by hepatic aldehyde oxidases.

     7-hydroxy Methotrexate (sodium salt) Chemical Structure
  24. GC42644 9-Deazaguanine 9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM). 9-Deazaguanine Chemical Structure
  25. GC49238 93-O17S A cationic lipidoid 93-O17S Chemical Structure
  26. GC42691 Aceclofenac ethyl ester A potential impurity found in commercial preparations of aceclofenac Aceclofenac ethyl ester Chemical Structure
  27. GC42692 Aceclofenac methyl ester A potential impurity in commercial preparations of aceclofenac Aceclofenac methyl ester Chemical Structure
  28. GC40645 Actarit 경구 활성 항류마티스 화합물인 Actarit는 II형 콜라겐 유발 관절염을 치료할 가능성이 있습니다. Actarit Chemical Structure
  29. GC45681 AKP-11 An S1P1 receptor agonist AKP-11 Chemical Structure
  30. GC46867 Apremilast-d5 Apremilast D5(CC-10004 D5)는 Apremilast라고 표시된 중수소입니다. Apremilast-d5 Chemical Structure
  31. GC45790 Artesunate-d4 Artesunate-d4는 Artesunate로 표시된 중수소입니다. Artesunate는 STAT-3와 수출 단백질 1(EXP1)의 억제제입니다. Artesunate-d4 Chemical Structure
  32. GC46895 Aurintricarboxylic Acid (ammonium salt) A protein synthesis inhibitor with diverse biological activities Aurintricarboxylic Acid (ammonium salt) Chemical Structure
  33. GC49646 Aurothioglucose (hydrate) A TrxR inhibitor Aurothioglucose (hydrate) Chemical Structure
  34. GC42877 AUY954 AUY954 is an orally bioavailable and selective agonist of the sphingosine-1-phosphate receptor 1 (S1P1; EC50 = 1.2 nM for stimulating GTPγS binding to S1P1 in CHO cells). AUY954 Chemical Structure
  35. GC42880 Avenanthramide-C methyl ester Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM). Avenanthramide-C methyl ester Chemical Structure
  36. GC49836 Benoxaprofen 베녹사프로펜(LRCL 3794)은 강력하고 오래 지속되는 항염증 및 해열 화합물입니다. Benoxaprofen Chemical Structure
  37. GC52326 Biotin-PEG4-LL-37 (human) (trifluoroacetate salt) A biotinylated and pegylated form of LL-37 Biotin-PEG4-LL-37 (human) (trifluoroacetate salt) Chemical Structure
  38. GC42953 BMS 345541 (trifluoroacetate salt) BMS 345541 is a cell permeable inhibitor of the IκB kinases IKKα and IKKβ (IC50s = 4 and 0.3 μM). BMS 345541 (trifluoroacetate salt) Chemical Structure
  39. GC46946 BPC 157 (acetate) A pentadecapeptide with diverse biological activities BPC 157 (acetate) Chemical Structure
  40. GC46983 C-170 C-170(C-170)은 강력하고 공유적인 STING 억제제입니다. C-170 Chemical Structure
  41. GC46984 C-171 C-171은 인터페론 유전자 자극제(STING)의 억제제입니다. C-171 Chemical Structure
  42. GC43007 C12 Galactosylceramide (d18:1/12:0) C12 Galactosylceramide is a bioactive sphingolipid. C12 Galactosylceramide (d18:1/12:0) Chemical Structure
  43. GC43076 C24 Phytosphingosine (t18:0/24:0) C24 Phytosphingosine (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C24 Phytosphingosine (t18:0/24:0) Chemical Structure
  44. GC43077 C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) C24:1 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids. C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) Chemical Structure
  45. GC47020 Calcium D-Glucarate (hydrate) The calcium salt form of D-glucaric acid Calcium D-Glucarate (hydrate) Chemical Structure
  46. GC49147 Carboxyphosphamide An inactive metabolite of cyclophosphamide Carboxyphosphamide Chemical Structure
  47. GC43176 CAY10575 CAY10575(화합물 8)는 IC50이 0.075 μ인 IKK2 억제제입니다. CAY10575 Chemical Structure
  48. GC47054 CAY10748 A STING agonist CAY10748 Chemical Structure
  49. GC45885 Chloroquine-d5 (phosphate) An internal standard for the quantification of chloroquine Chloroquine-d5 (phosphate) Chemical Structure
  50. GC52351 Citrullinated α-Enolase (R8 + R14) (1-19)-biotin Peptide A biotinylated and citrullinated α-enolase peptide Citrullinated α-Enolase (R8 + R14) (1-19)-biotin Peptide Chemical Structure
  51. GC52363 Citrullinated Histone H3 (R2 + R8 + R17) (2-22)-biotin Peptide

    A biotinylated and citrullinated histone H3 peptide

     Citrullinated Histone H3 (R2 + R8 + R17) (2-22)-biotin Peptide Chemical Structure
  52. GC52367 Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide A biotinylated and citrullinated mutant vimentin peptide Citrullinated Vimentin (G146R) (R144 + R146) (139-159)-biotin Peptide Chemical Structure
  53. GC52370 Citrullinated Vimentin (R144) (139-159)-biotin Peptide A biotinylated and citrullinated vimentin peptide Citrullinated Vimentin (R144) (139-159)-biotin Peptide Chemical Structure
  54. GC49680 Clobetasone Propionate A corticosteroid Clobetasone Propionate Chemical Structure
  55. GC18572 Concanavalin A

    콘카나마이신 A는 Streptomyces diastatochromogenes에서 분리된 매크로라이드 항생물질인 콘카나마이신 가족에 속하며, 고도로 활성화되고 선택적으로 세포질 프로톤-ATPase (v-[H+]ATPase)를 억제하는 항생제입니다.

     Concanavalin A Chemical Structure
  56. GC45413 Cridanimod (sodium salt)   Cridanimod (sodium salt) Chemical Structure
  57. GC45614 Cryogenine An alkaloid with anti-inflammatory activity Cryogenine Chemical Structure
  58. GC47128 CU-32 A cGAS inhibitor CU-32 Chemical Structure
  59. GC47129 CU-76 A cGAS inhibitor CU-76 Chemical Structure
  60. GC43339 Cyclic di-AMP (sodium salt) Cyclic di-AMP (c-di-AMP) is a second messenger produced by bacteria but not by mammals. Cyclic di-AMP (sodium salt) Chemical Structure
  61. GC19526 Cyclic di-GMP (sodium salt) Cyclic di-GMP(나트륨 염)는 STING 작용제이자 운동성, 독성, 생물막 형성 및 세포 주기 진행을 비롯한 세균 성장 및 행동의 다양한 측면을 조정하는 세균 2차 전달자입니다. Cyclic di-GMP(sodium salt)는 항암 세포 증식 활성을 가지며, 또한 CD4 수용체 발현 증가 및 세포 주기 정지를 유도합니다. Cyclic di-GMP(나트륨염)는 암 연구에 사용할 수 있습니다. Cyclic di-GMP (sodium salt) Chemical Structure
  62. GC43340 Cyclic di-IMP (sodium salt) Cyclic di-IMP (sodium salt) (c-di-IMP) is a synthetic second messenger structurally related to the bacterial second messengers cyclic di-GMP and cyclic di-AMP. Cyclic di-IMP (sodium salt) Chemical Structure
  63. GC48397 Cyclic di-UMP (sodium salt) A pyrimidine-containing CDN Cyclic di-UMP (sodium salt) Chemical Structure
  64. GC47148 Cyclophosphamide-d4 Cyclophosphamide-d4는 Cyclophosphamide로 표시된 중수소입니다. 사이클로포스파미드는 면역억제제인 항종양 활성을 갖는 질소 머스타드와 화학적으로 관련된 합성 알킬화제입니다. Cyclophosphamide-d4 Chemical Structure
  65. GC47193 Desethyl Hydroxychloroquine-d4 An internal standard for the quantification of desethyl hydroxychloroquine Desethyl Hydroxychloroquine-d4 Chemical Structure
  66. GC43444 Diclofenac Acyl-β-D-Glucuronide Diclofenac acyl-β-D-glucuronide is an active metabolite of diclofenac and the predominant metabolite in rat. Diclofenac Acyl-β-D-Glucuronide Chemical Structure
  67. GC47212 Diclofenac amide A prodrug form of diclofenac Diclofenac amide Chemical Structure
  68. GC43447 Diclofenac methyl ester Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac. Diclofenac methyl ester Chemical Structure
  69. GC47213 Diclofenac-d4 An internal standard for the quantification of diclofenac Diclofenac-d4 Chemical Structure
  70. GC40867 Diflorasone Diacetate 디플로라손 디아세테이트는 국소 또는 국소 약제로 사용되는 항염증 스테로이드 화합물입니다. Diflorasone Diacetate Chemical Structure
  71. GC43494 DL-threo-PDMP (hydrochloride) DL-threo PDMP is a mixture of ceramide analogs that contains two of the four possible stereoisomers of PDMP : D-threo (1R,2R) and L-threo (1S,2S) PDMP. DL-threo-PDMP (hydrochloride) Chemical Structure
  72. GC52334 ENPP1 Inhibitor 4e An ENPP1 inhibitor ENPP1 Inhibitor 4e Chemical Structure
  73. GC52303 Ethyl Mycophenolate A potential impurity found in commercial preparations of mycophenolate mofetil Ethyl Mycophenolate Chemical Structure
  74. GC47323 Etofenamate-d4 An internal standard for the quantification of etofenamate Etofenamate-d4 Chemical Structure
  75. GC40565 Feprazone Phenylbutazone의 유사체인 Feprazone(DA2370; Prenazone)은 진통 및 해열 활성이 있는 비스테로이드성 항염증제입니다. Feprazone Chemical Structure
  76. GC46148 Filgotinib-d4 Filgotinib-d4(GLPG0634-d4)는 Filgotinib으로 표시된 중수소입니다. 필고티닙(GLPG0634)은 JAK1, JAK2, JAK3 및 TYK2에 대해 IC50이 각각 10nM, 28nM, 810nM 및 116nM인 선택적 JAK1 억제제입니다. Filgotinib-d4 Chemical Structure
  77. GC47366 Flurbiprofen-d3 An internal standard for the quantification of flurbiprofen Flurbiprofen-d3 Chemical Structure
  78. GC49074 Forphenicine A bacterial metabolite and an inhibitor of alkaline phosphatase Forphenicine Chemical Structure
  79. GC52487 Ganglioside GM4 (chicken egg) (ammonium salt) A sphingolipid Ganglioside GM4 (chicken egg) (ammonium salt) Chemical Structure
  80. GC43804 Halofuginone (hydrochloride) Halofuginone is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D. Halofuginone (hydrochloride) Chemical Structure
  81. GC49496 Homocitrulline-d3 An internal standard for the quantification of homocitrulline Homocitrulline-d3 Chemical Structure
  82. GC47445 Hydroxychloroquine-d4 (sulfate) An internal standard for the quantification of hydroxychloroquine Hydroxychloroquine-d4 (sulfate) Chemical Structure
  83. GC43894 IKK2 Inhibitor VI

    Inhibitor of NF-κB kinase 2 (IKK2, also known as IKKβ) acts as part of an IKK complex in the canonical NF-κB pathway, phosphorylating inhibitors of NF-κB (IκBs) to initiate signaling.

     IKK2 Inhibitor VI Chemical Structure
  84. GC40901 Isogarcinol Isogarcinol is a natural polyisoprenylated benzophenone first isolated from plant species in the genus Garcinia. Isogarcinol Chemical Structure
  85. GC52291 KAS 08 A STING activator KAS 08 Chemical Structure
  86. GC52394 LC10 A lipidoid derivative of lithocholic acid LC10 Chemical Structure
  87. GC47552 Leflunomide-d4 Leflunomide-d4(HWA486-d4)는 Leflunomide로 표지된 중수소입니다. 레플루노미드는 피리미딘 합성 억제제로 디하이드로오로테이트 탈수소효소(DHODH)를 억제하며 질병 조절 항류마티스 약물로 작용합니다. Leflunomide-d4 Chemical Structure
  88. GC44078 LL-37 amide (trifluoroacetate salt) LL-37 is a cationic and α-helical antimicrobial peptide expressed in human bone marrow, testis, granulocytes, and gingival epithelium and is upregulated in psoriatic lesions. LL-37 amide (trifluoroacetate salt) Chemical Structure
  89. GC41452 Luteoloside Luteoloside is a flavonoid that has been found in many Chinese herbs with diverse biological activities. Luteoloside Chemical Structure
  90. GC49916 Lys-(Des-Arg9, Leu8)-Bradykinin (trifluoroacetate salt) A bradykinin B1 receptor antagonist Lys-(Des-Arg9, Leu8)-Bradykinin (trifluoroacetate salt) Chemical Structure
  91. GC47649 Methotrexate (hydrate) A folic acid and aminopterin derivative Methotrexate (hydrate) Chemical Structure
  92. GC47650 Methotrexate-d3 An internal standard for the quantification of methotrexate Methotrexate-d3 Chemical Structure
  93. GC45998 Mitoxantrone-d8 Mitoxantrone-d8(mitozantrone-d8)은 Mitoxantrone이라고 표시된 중수소입니다. 미톡산트론은 토포이소머라제 II 억제제이며 또한 8.5μM의 IC50으로 단백질 키나제 C(PKC) 활성을 억제합니다. Mitoxantrone-d8 Chemical Structure
  94. GC52419 MOG (35-55) (mouse, rat) (trifluoroacetate salt) An MOG antigen peptide MOG (35-55) (mouse, rat) (trifluoroacetate salt) Chemical Structure
  95. GC47712 Mycophenolate Mofetil-d4 Mycophenolate Mofetil-d4는 Mycophenolate Mofetil이라고 표시된 중수소입니다. 미코페놀레이트 모페틸(RS 61443)은 미코페놀산의 모르폴리노에틸에스테르 전구약물입니다. Mycophenolate mofetil은 IMPDH(inosine monophosphate dehydrogenase)의 억제를 통해 새로운 퓨린 합성을 억제합니다. Mycophenolate mofetil은 T 세포와 B 세포를 모두 포함하여 항체 형성을 방지하는 선택적 림프구 항증식 효과를 나타냅니다. Mycophenolate Mofetil-d4 Chemical Structure
  96. GC52385 Myelin Basic Protein (85-99) Peptide Antagonist (trifluoroacetate salt) An MBP (85-99) antagonist Myelin Basic Protein (85-99) Peptide Antagonist (trifluoroacetate salt) Chemical Structure
  97. GC44257 Myelin Basic Protein (87-99) (human, bovine, rat) (trifluoroacetate salt) Myelin basic protein (MPB) (87-99) is an encephalitogenic peptide. Myelin Basic Protein (87-99) (human, bovine, rat) (trifluoroacetate salt) Chemical Structure
  98. GC40298 N-acetyl-5-Aminosalicylic Acid N-acetyl-5-Aminosalicylic acid is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid and its prodrug form, sulfasalazine. N-acetyl-5-Aminosalicylic Acid Chemical Structure
  99. GC44388 NF-κB Control NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. NF-κB Control Chemical Structure
  100. GC48985 NF-κB Inhibitor (trifluoroacetate salt) A cell-permeable peptide that blocks nuclear import of NF-κB NF-κB Inhibitor (trifluoroacetate salt) Chemical Structure
  101. GC18895 NIBR0213 NIBR-0213은 실험적 자가면역 뇌척수염에서 효능이 있는 강력하고 선택적인 S1P1 길항제입니다. NIBR0213 Chemical Structure

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