Innate Immunity
Products for Innate Immunity
- Cat.No. 상품명 정보
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GC45206
α-GalCer analog 8
α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide.
- GC48292 α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt) α-MSH(⋱-멜라닌 세포 자극 호르몬) TFA는 내인성 신경 펩티드이며 항염 및 해열 활성을 갖는 내인성 멜라노코르틴 수용체 4(MC4R) 작용제입니다.
- GC41499 α-Phellandrene α-Phellandrene is a cyclic monoterpene that has been found in various plants, including Cannabis, and has diverse biological activities.
- GC48920 β-Carboline-1-carboxylic Acid An alkaloid with diverse biological activities
- GC48298 β-Defensin-2 (human) (trifluoroacetate salt) An antimicrobial peptide
- GC45230 β-Defensin-3 (human) (trifluoroacetate salt) β-Defensin-3 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.
- GC45231 β-Defensin-4 (human) (trifluoroacetate salt) β-Defensin-4 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.
- GC52010 (±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid An oxylipin gut microbiota metabolite
- GC40466 (±)11(12)-EET (±)11(12)-EET는 NLRP3 인플라마좀 억제제입니다.
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GC40802
(±)12(13)-DiHOME
(±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.
- GC41288 (±)17(18)-EpETE-Ethanolamide (±)17(18)-EpETE-Ethanolamide is an ω-3 endocannabinoid epoxide.
- GC40362 (±)18-HEPE (±)18-HEPE is produced by non-enzymatic oxidation of EPA.
- GC41655 (±)19(20)-EDP Ethanolamide (±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively).
- GC40801 (±)9(10)-DiHOME (±)9(10)-DiHOME은 9,10-DiHOME의 라세미체입니다.
- GC45272 (-)-Rasfonin (-)-Rasfonin은 곰팡이 2차 대사 산물이며 작은 G 단백질 Ras를 억제합니다. (-)-Rasfonin은 ACHN 세포(신장암 세포주)에서 세포자살, 괴사 및 자가포식을 유도합니다.
- GC41712 (R)-3-hydroxy Myristic Acid Lipopolysaccharides (LPS) are components of the cell walls of Gram-negative bacteria.
- GC46352 (S)-DO271 An inactive control for DO264
- GC41740 (S)-p38 MAPK Inhibitor III (S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro).
- GC49768 1,1’-Ethylidene-bis-(L-tryptophan) A potential impurity found in commercial preparations of L-tryptophan
- GC41855 1,3-Distearoyl-2-Oleoyl-rac-glycerol 1,3-Distearoyl-2-oleoyl-rac-glycerol is a triacylglycerol that contains stearic acid at the sn-1 and sn-3 positions and oleic acid at the sn-2 position.
- GC49294 1-(4-Chlorobenzhydryl)piperazine An inactive metabolite of meclizine and chlorcyclizine
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GC41986
1-Arachidonoyl Lysophosphatidic Acid (ammonium salt)
1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position.
- GC52186 1-Docosahexaenoyl-2-hydroxy-sn-glycero-3-PC
- GC46481 1-Hydroxyphenazine A P. aeruginosa virulence factor
- GC41998 1-Methyl-4-imidazoleacetic Acid (hydrochloride) 1-Methyl-4-imidazoleacetic acid (MIMA) is a stable metabolite of histamine that is produced by the oxidation of the primary metabolite, N-methylhistamine.
- GC40910 1-Oleoyl-2-hydroxy-sn-glycero-3-PE 1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine.
- GC42026 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC는 풍부한 생식선 LPC(리소포스파티딜콜린)입니다.
- GC42035 1-Palmitoyl-2-Stearoyl-3-Oleoyl-rac-glycerol 1-Palmitoyl-2-stearoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains palmitic, stearic, and oleic acid at the sn-1, sn-2, and sn-3 positions, respectively.
- GC45693 1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications
- GC49730 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 An internal standard for the quantification of 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE
- GC41331 1-Stearoyl-2-hydroxy-sn-glycero-3-PC 1-Stearoyl-2-hydroxy-sn-glycero-3-PC is a saturated 18:0 lysophosphatidylcholine found in plasma and oxidized LDL that is thought to play a role in inflammatory diseases and atherosclerosis.
- GC46498 1-Stearoyl-d35-2-hydroxy-sn-glycero-3-PC An internal standard for the quantification of 1-stearoyl-2-hydroxy-sn-glycero-3-PC
- GC40971 10(S),17(S)-DiHDHA 10(S),17(S)-DiHDHA(신경 조직에서 생성될 때 뉴로프로텍틴 D1이라고도 함)는 DHA에서 파생된 디하이드록시 지방산으로 강력한 보호 및 항염 활성을 나타냅니다.
- GC41875 11(Z),14(Z)-Eicosadienoic Acid methyl ester 11(Z),14(Z)-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid, a naturally occurring PUFA.
- GC41144 11-trans Leukotriene C4 11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4.
- GC52343 113-O12B An ionizable cationic lipidoid
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GC18637
11β-Prostaglandin F2α
11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo.
- GC40447 12(R)-HETE Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid.
- GC41123 12-epi Leukotriene B4 Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes.
- GC41096 12-oxo Leukotriene B4 Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway.
- GC49912 13C20,15N10-Cyclic di-GMP (sodium salt) An internal standard for the quantification of cyclic di-GMP
- GC41100 14,15-dehydro Leukotriene B4 Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway.
- GC41145 14,15-Leukotriene C4 Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes.
- GC41148 14,15-Leukotriene D4 14,15-Leukotriene D4 (14,15-LTD4) is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-lipoxygenases (15- and 12-LOs) on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates.
- GC41150 14,15-Leukotriene E4 Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes.
- GC41164 15(R)-15-methyl Prostaglandin D2 15(R)-15-methyl Prostaglandin D2 (15(R)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2.
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GC41415
15(R)-Lipoxin A4
Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function.
- GC40451 15(S)-HETE 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway.
- GC49178 17(R)-Protectin D1 An aspirin-triggered epimer of protectin D1
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GC41951
17(R)-Resolvin D1
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.
- GC41227 17(R)-Resolvin D1 methyl ester 17(R)-Resolvin D1 (17(R)-RvD1) is an aspirin-triggered epimer of RvD1 that reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with equipotency to RvD1 (EC50 = ~30 nM).
- GC45307 17(R)-Resolvin D3
- GC41208 17(S)-HDHA 17(S)-HDHA is a primary mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, and mouse brain.
- GC40975 17(S)-HpDHA 17(S)-HpDHA is a mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, human glial cells, and mouse brain.
- GC41160 1a,1b-dihomo Prostaglandin E2 1a,1b-dihomo Prostaglandin E2 (PGE2) is a rare polyunsaturated fatty acid first identified in extracts of sheep vesicular gland microsomes, known to contain COX, incubated with adrenic acid.
- GC42080 2'2'-cGAMP (sodium salt) 2'2'-cGAMP is a synthetic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds.
- GC42123 2-Aminopurine (hydrochloride) 2-아미노퓨린(염산염)은 구아노신의 형광 유사체입니다.
- GC42135 2-chloro Palmitic Acid 염증성 지질 매개체인 2-클로로팔미트산은 단백질 팔미토일화를 방해하고, ER-스트레스 마커를 유도하고, ER ATP 함량을 감소시키며, IL-6 및 IL-8.2-클로로팔미트산의 전사 및 분비를 활성화합니다. 막 전위를 유도하고 프로카스파제-3 및 PARP 절단을 유도합니다. 2-클로로 팔미트산은 혈액-뇌 장벽(BBB)을 가로질러 인간 뇌 내피 세포주 hCMEC/D3에서 ER- 및 미토콘드리아 기능을 손상시킬 수 있습니다.
- GC42136 2-chloro Stearic Acid 2-chloro Stearic acid is a bioactive fatty acid that accumulates in primary human monocytes and neutrophils as well as murine neutrophils stimulated with phorbol 12-myristate 13-acetate.
- GC42082 20-carboxy Leukotriene B4 20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils.
- GC41421 20-hydroxy Leukotriene B4 20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils.
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GC40571
24(S),25-epoxy Cholesterol
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.
- GC48482 28-Acetylbetulin A lupane triterpenoid with anti-inflammatory and anticancer activities
- GC49122 3′-deoxy Thymidine An antiviral nucleoside analog
- GC42242 3'-sulfo Galactosylsphingosine (ammonium salt) 3'-sulfo Galactosylsphingosine is a form of sulfatide that is lacking the fatty acyl group.
- GC46583 3-Amino-2,6-Piperidinedione An active metabolite of (±)-thalidomide
- GC45354 4β-Hydroxywithanolide E 4β, Physalis peruviana L.에서 분리된 하이드록시위타놀라이드 E.
- GC42338 4-Aminobenzoic Acid hydrazide 4-Aminobenzoic Acid hydrazide는 IC50이 0.3 μ인 비가역적 MPO myeloperoxidase 억제제입니다.
- GC46630 4-CPPC A MIF-2 inhibitor
- GC42369 4-Deoxypyridoxine (hydrochloride) 4-Deoxypyridoxine (4-DPD) is a vitamin B6 antimetabolite with diverse biological activities.
- GC42374 4-epi-Chlortetracycline (hydrochloride) Chlortetracycline is an analog of tetracycline, a broad spectrum antibiotic.
- GA20418 4-Hydroxy-hippuric acid Polyphenol metabolite.
- GC46673 4-octynyl Itaconate 4-옥티닐 Itaconate(ITalk)는 살아있는 세포에서 Itaconation의 정량적 및 부위 특이적 화학단백체 프로파일링을 위한 특정 생체 직교 프로브입니다.
- GC48381 5'-pApA (sodium salt) A linearized form of cyclic di-AMP
- GC48375 5'-pGpG (sodium salt) A linearized form of cyclic di-GMP
- GC41126 5(S),12(S)-DiHETE 5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid.
- GC41127 5(S),15(S)-DiHETE 5(S),15(S)-DiHETE는 \5(S),15(S)-DiHETE is an “activated” intermediate, inhibits platelet aggregation with an IC50 of 1.3 μM.en_ko_2021q1.md
- GC49827 5-Androstenetriol An active metabolite of DHEA
- GC45357 5-Chlorouracil
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GC40380
5-OxoETE
5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils by a specific dehydrogenase.
- GC49676 6β-hydroxy Budesonide A metabolite of budesonide
- GC45772 6(5H)-Phenanthridinone An inhibitor of PARP1 and 2
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GC40202
7α-hydroxy Cholesterol-d7
7α-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7α-hydroxy cholesterol by GC- or LC-MS.
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GC46241
7-keto Cholesterol-d7
7-keto Cholesterol is a bioactive sterol and a major oxysterol component of oxidized LDL
- GC48880 7-Methoxyflavone 7-Methoxyflavone은 Zornia brasiliensis에서 분리된 화합물입니다.
- GC41136 8(S),15(S)-DiHETE 8(S),15(S)-DiHETE is formed when 15(S)-HETE is subjected to further oxidation by 15-LO.
- GC42623 8-Bromoguanosine 8-Bromoguanosine is a brominated derivative of guanosine.
- GC46748 9(E),11(E)-12-nitro Conjugated Linoleic Acid A nitrated fatty acid
- GC46749 9(E),11(E)-9-nitro Conjugated Linoleic Acid A nitrated fatty acid
- GC46757 9(Z),11(E)-Conjugated Linoleic Acid (sodium salt) An isomer of linoleic acid
- GC49238 93-O17S A cationic lipidoid
- GC45960 9c(i472) 9c(i472)는 IC50 값이 0.19 μ인 15-LOX-1(15-리폭시게나제-1)의 강력한 억제제입니다.
- GC42683 Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human neutrophil elastase (kcat/Km = 531 mM-1s-1).
- GC52499 Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp (trifluoroacetate salt) A sensitive substrate for neutrophil elastase
- GC42684 Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt) Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human proteinase 3 (kcat/Km = 1,570 mM-1s-1).
- GC42685 Ac-ANW-AMC Ac-ANW-AMC는 면역프로테아좀에 대한 형광 기질입니다.
- GC49704 Ac-FLTD-CMK (trifluoroacetate salt) An inhibitor of caspase-1, -4, -5, and -11
- GC49263 Ac2-26 (human) (ammonium salt) An annexin A1-mimetic peptide
- GC46798 Adapalene-d3 An internal standard for the quantification of adapalene
- GC42763 Alamethicin F50 Alamethicin F50 is a peptaibol isolated from Trichoderma.