(S)-Higenamine hydrobromide |
| Catalog No.GC62751 |
(S)-Higenamine ((S)-Norcoclaurine) 히드로브로마이드, Higenamine의 S-거울상 이성질체는 벤질이소퀴놀린 알칼로이드 생합성의 진입 화합물입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 105990-27-0
Sample solution is provided at 25 µL, 10mM.
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(S)-Higenamine ((S)-Norcoclaurine) hydrobromide, a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine hydrobromide is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS)[1].
The biosynthetic pathway leading to benzylisoquinoline alkaloids originates from the enzyme-catalyzed condensation of dopamine and 4-hydrophenylacetaldehyde to yield (S)-norcoclaurine. Both substrates are secondary metabolites derived from the decarboxylation/hydroxylation/deamination of tyrosine[1].
[1]. Minami H, et al. Functional analysis of norcoclaurine synthase in Coptis japonica. J Biol Chem. 2007;282(9):6274‐6282.
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