>>Signaling Pathways>> DNA Damage/DNA Repair>> DNA Alkylator/Crosslinker>>(S)-Seco-Duocarmycin SA

(S)-Seco-Duocarmycin SA

Catalog No.GC60421

(S)-Seco-Duocarmycin SA는 DNA 알킬화제로서 암세포에 세포독성이 있으며 항체-약물 접합체에 대한 ADC 세포독소로 작용합니다.

Products are for research use only. Not for human use. We do not sell to patients.

(S)-Seco-Duocarmycin SA Chemical Structure

Cas No.: 152785-82-5

Size 가격 재고 수량
5mg
US$1,530.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

(S)-Seco-Duocarmycin SA is a DNA alkylator, cytotoxic to cancer cells, and acts as a ADC cytotoxin for antibody-drug conjugates[1].

[1]. Tichenor MS, et al. Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity. J Am Chem Soc. 2007 Sep 5;129(35):10858-69.

리뷰

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