(S)-Verapamil D7 hydrochloride (Synonyms: (S)-(-)-Verapamil D7 hydrochloride) |
| Catalog No.GC60425 |
(S)-Verapamil D7 염산염((S)-(-)-Verapamil D7 염산염)은 (S)-Verapamil 염산염으로 표지된 중수소입니다. (S)-Verapamil 염산염(S(-)-Verapamil 염산염)은 MRP1에 의한 류코트리엔 C4(LTC4)와 칼세인 수송을 억제합니다. (S)-Verapamil 염산염은 잠재적으로 내성이 있는 종양 세포를 죽입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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(S)-Verapamil D7 hydrochloride ((S)-(-)-Verapamil D7 hydrochloride) is a deuterium labeled (S)-Verapamil hydrochloride. (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells[1][2].
[1]. Perrotton T, et al. (R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1. J Biol Chem. 2007 Oct 26;282(43):31542-8. Epub 2007 Jul 22. [2]. Tannergren C, et al. St John's wort decreases the bioavailability of R- and S-verapamil through induction of the first-pass metabolism. Clin Pharmacol Ther. 2004 Apr;75(4):298-309.
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