UNC0379 |
| Catalog No.GC16741 |
UNC0379는 IC50이 7.3μM, KD 값이 18.3μM인 라이신 메틸트랜스퍼라제 SETD8(KMT5A)의 선택적 기질 경쟁적 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1620401-82-2
Sample solution is provided at 25 µL, 10mM.
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UNC0379 is a selective, substrate-competitive inhibitor of lysine methyltransferase SETD8 (KMT5A) with an IC50 of 7.3 μM; selective over 15 other methyltransferases[1].
References:
[1]. Ma A, et al. Discovery of a Selective, Substrate-Competitive Inhibitor of the Lysine Methyltransferase SETD8. J Med Chem. 2014 Aug 14;57(15):6822-33.
Average Rating: 5 (Based on Reviews and 40 reference(s) in Google Scholar.)
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