(-)-Voacangarine (Synonyms: NSC 306219, (-)-Voacristine) |
| Catalog No.GC40076 |
(-)-Voacangarine is an indole alkaloid originally isolated from V.
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Cas No.: 545-84-6
Sample solution is provided at 25 µL, 10mM.
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(-)-Voacangarine is an indole alkaloid originally isolated from V. africana that is cytotoxic to HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 cells (IC50s = 20 µg/ml). It is cytostatic to wild-type S. cerevisiae and cytotoxic to δrad3-e5 and δrad6-1 mutant S. cerevisiae, which are defective in DNA strand break repair and the mutagenic repair pathway, respectively.
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