L-156,602 (Synonyms: PD 124966) |
Catalog No.GC18900 |
L-156,602 is an antagonist of the complement component 5A (C5a) receptor (IC50 = 1.7 ug/L in a radioligand binding assay using neutrophil membranes).
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Cas No.: 125228-51-5
Sample solution is provided at 25 µL, 10mM.
L-156,602 is an antagonist of the complement component 5A (C5a) receptor (IC50 = 1.7 ug/L in a radioligand binding assay using neutrophil membranes). It is also a cyclic depsipeptide antibiotic that is active against Gram-positive bacteria. L-156,602 has anti-inflammatory activity in mice, decreasing inflammation induced by muramyl dipeptide (MDP) when administered at a dose of 0.5 mg/kg and by concanavalin A at doses of 0.25 and 0.5 mg/kg.
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