L-(+)-Ergothioneine (Synonyms: 2Mercaotohistidine Betaine, NSC 7175) |
| Catalog No.GC44019 |
L-(+)-Ergothioneine, an imidazole-2-thione derivative of histidine betaine, is synthesized by certain bacteria and fungi.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 497-30-3
Sample solution is provided at 25 µL, 10mM.
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L-(+)-Ergothioneine is a naturally-occurring amino acid derived from histidine via hercynine. Ergothioneine is a stable antioxidant that scavenges and detoxifies free radicals and oxidants, increases intracellular thiol levels, controls nuclear factor-κB activation, and inhibits inflammatory gene expression. In addition, it inhibits the peroxynitrite-dependent nitration of nitrotyrosine, blocks oxidative DNA damage and cell death, and prevents the formation of xanthine and hypoxanthine. Ergothioneine is transported by the organic cation/carnitine transporter 1, which has been linked with autoimmune diseases, including rheumatoid arthritis and Crohn's disease.
Average Rating: 5 (Based on Reviews and 23 reference(s) in Google Scholar.)
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