Hydroxy/Hydroperoxy/Epoxy/Oxo Eicosanoids
Products for Hydroxy/Hydroperoxy/Epoxy/Oxo Eicosanoids
- Cat.No. Product Name Information
- GC49439 (±)11(12)-DiHET MaxSpec® Standard A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications
- GC40386 (±)11(12)-EpETE Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETE) by several cytochrome P450 isoforms.
- GC41143 (±)11,12-DiHETE (±)11,12-DiHETE is a dihydroxy metabolite of EPA produced by cytochrome P450-mediated epoxide formation and subsequent hydrolysis by epoxide hydrolase.
- GC40428 (±)11-HEDE (±)11-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.
- GC40387 (±)11-HEPE (±)11-HEPE is produced by non-enzymatic oxidation of eicosapentaenoic acid.
- GC40467 (±)11-HETE (±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid.
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GC40359
(±)12-HEPE
(±)12-HEPE is produced by non-enzymatic oxidation of EPA.
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GC40429
(±)12-HETE
(±)12-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid.
- GC41115 (±)12-HpETE (±)12-HpETE is one of the six monohydroperoxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid and consists of an equal mixture of the R and S isomers.
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GC40430
(±)14(15)-EET
(±)14(15)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450.
- GC41651 (±)14(15)-EET-SI Arachidonic acid is metabolized in the vascular endothelium to epoxytrienoic acids (EETs or EpETrEs) by cytochrome P450 enzymes.
- GC41652 (±)14(15)-EpEDE 8,11,14-Eicosatrienoic acid, also known as dihomo-γ-linolenic acid, is a polyunsaturated fatty acid (PUFA) produced from γ-linolenic acid by the action of fatty acid elongases.
- GC40360 (±)14(15)-EpETE EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators.
- GC40420 (±)15-HEDE (±)15-HEDE is produced by non-enzymatic oxidation of 11,14-eicosadienoic acid.
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GC40361
(±)15-HEPE
(±)15-HEPE is produced by non-enzymatic oxidation of EPA.
- GC41117 (±)17(18)-DiHETE Eicosapentaenoic acid is an ω-3 fatty acid abundantly available in marine organisms.
- GC41288 (±)17(18)-EpETE-Ethanolamide (±)17(18)-EpETE-Ethanolamide is an ω-3 endocannabinoid epoxide.
- GC40362 (±)18-HEPE (±)18-HEPE is produced by non-enzymatic oxidation of EPA.
- GC40436 (±)18-HETE (±)18-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid.
- GC40437 (±)5(6)-DiHET lactone 5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET.
- GC41119 (±)5(6)-DiHETE Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.
- GC40363 (±)5(6)-DiHETE lactone Eicosapentaenoic acid is metabolized, in part, through cytochrome P450-catalyzed epoxidation followed by conversion to the vicinal diols by epoxide hydrolases.
- GC41319 (±)5(6)-EpETE methyl ester (±)5(6)-EpETE methyl ester is a derivative of 5(6)-EpETE which is stable enough to ship and handle routinely.
- GC40364 (±)5-HEPE (±)5-HEPE is produced by non-enzymatic oxidation of EPA.
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GC40439
(±)5-HETE
(±)5-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid.
- GC40837 (±)5-HETE methyl ester (±)5-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid.
- GC40272 (±)8(9)-DiHET Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity.
- GC40421 (±)8(9)-EE-14(Z)-E (±)14(15)-EE-8(Z)-E is a potent vasodilator in bovine coronary arteries.
- GC40365 (±)8(9)-EpETE Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms.
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GC41120
(±)8,9-DiHETE
(±)8,9-DiHETE is a major metabolite of the 20:5 ω-3 fatty acid eicosapentaenoic acid.
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GC40366
(±)8-HEPE
(±)8-HEPE is produced by non-enzymatic oxidation of EPA.
- GC40367 (±)9-HEPE (±)9-HEPE is produced by non-enzymatic oxidation of EPA.
- GC40443 (±)9-HETE (±)9-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid.
- GC40444 (5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic Acid (5Z,11Z,15R)-15-Hydroxyeicosa-5,11-dien-13-ynoic acid is a stable isomer of 15(S)-HETE, a major arachidonic acid metabolite from the 15-lipoxygenase pathway.
- GC40422 11(R)-HEDE 11(R)-HEDE is produced from 11Z,14Z-eicosadienoic acid by COX in a lipoxygenase-type reaction.
- GC40368 11(R)-HEPE 11(R)-HEPE is produced by the oxidation of EPA by 11(R)-LO.
- GC40445 11(R)-HETE 11(R)-HETE is biosynthesized by 11(R)-LOs of the sea urchin, S.
- GC40423 11(S)-HEDE 11(S)-HEDE is isolated by the chromatographic resolution of (±)11-HEDE.
- GC40369 11(S)-HEPE 11(S)-HEPE is a monohydroxy fatty acid derived from EPA, theoretically by the action of COX.
- GC40446 11(S)-HETE 11(S)-HETE is an oxylipin and the (S) enantiomer of 11(R)-HETE. It is formed non-enzymatically from arachidonic acid.
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GC40370
12(R)-HEPE
12(R)-HEPE is a monohydroxy fatty acid synthesized from EPA by the eggs of the sea urchin, S.
- GC40447 12(R)-HETE Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid.
- GC40371 12(S)-HEPE 12(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 12-LO.
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GC40448
12(S)-HETE
12(S)-HETE is the predominant lipoxygenase product of mammalian platelets.
- GC41882 12(S)-HETrE 12(S)-HETrE is produced by 12-lipoxygenase oxidation of dihomo-γ-linolenic acid (DGLA).
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GC41095
12(S)-HpEPE
12(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 12-lipoxygenase on eicosapentaenoic acid.
- GC40372 12-OxoETE 12-OxoETE is synthesized by human platelets and Aplysia nervous tissue after incubation with arachidonic acid.
- GC40424 14,15-EE-5(Z)-E Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity.
- GC40425 14,15-EE-8(Z)-E Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity.
- GC46438 14S(15R)-EET A cytochrome P450 metabolite of arachidonic acid
- GC40426 15(R)-HEDE 15(R)-HEDE is isolated by the chromatographic resolution of (±)15-HEDE.
- GC40373 15(S)-HEPE 15(S)-HEPE is a monohydroxy fatty acid synthesized from EPA by the action of 15-LO.
- GC40451 15(S)-HETE 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway.
- GC40839 15(S)-HETE methyl ester 15(S)-HETE methyl ester is a synthetic derivative of 15(S)-HETE, a major arachidonic acid metabolite from the 15-lipoxygenase pathway.
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GC41403
15(S)-HpEDE
15(S)-HpEDE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosadienoic acid.
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GC41101
15(S)-HpEPE
15(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 15-lipoxygenase on eicosapentaenoic acid.
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GC41124
15(S)-HpETE
15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid.
- GC41940 15-OxoEDE 15-OxoEDE is produced by the oxidation of 15-HEDE.
- GC40376 15-OxoETE 15-OxoETE is produced by oxidation of the 15-hydroxyl of 15-HETE.
- GC49356 17(S)-HDoTE A metabolite of adrenic acid
- GC40457 19(R)-HETE 19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II.
- GC40458 19(S)-HETE 19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II.
- GC46475 19R(20S)-EpDPA A DHA metabolite
- GC41388 2-hydroxy Arachidic Acid 2-hydroxy Arachidic acid is a hydroxylated fatty acid that has been found in pasture grass (S.
- GC42162 2-hydroxy Arachidic Acid methyl ester 2-hydroxy Arachidic acid methyl ester is a hydroxylated fatty acid methyl ester that has been found in sediment samples from the Harney River and in petroleum ether extracts of I.
- GC42083 20-HETE Ethanolamide Arachidonoyl ethanolamide (AEA) is an endogenous lipid neurotransmitter with cannabinergic activity, binding both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors.
- GC42084 20-hydroxy Arachidic Acid methyl ester 20-hydroxy Arachidic acid methyl ester is a hydroxylated fatty acid methyl ester that has been found in P.
- GC40459 5(R)-HETE 5(R)-HETE is a rare lipoxygenase product of arachidonic acid.
- GC41126 5(S),12(S)-DiHETE 5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid.
- GC41127 5(S),15(S)-DiHETE 5(S),15(S)-DiHETE is synthesized by 15-LO from 5(S)-HETE.
- GC41128 5(S),6(R)-11-trans DiHETE 5(S),6(R)-11-trans DiHETE is a C-11 double bond isomer of 5(S),6(R)-DiHETE that is formed by the enzymatic isomerization of 5(S),6(R)-DiHETE by a membrane bound factor.
- GC41129 5(S),6(R)-DiHETE 5(S),6(R)-DiHETE is a dihydroxy polyunsaturated fatty acid and a nonenzymatic hydrolysis product of leukotriene A4 (LTA4).
- GC41131 5(S),6(S)-DiHETE 5(S),6(S)-DiHETE is one of the four diastereomeric 5,6-dihydroxy acids produced from the non-enzymatic hydrolysis of LTA4.
- GC40378 5(S)-HEPE 5(S)-HEPE is produced by 5-lipoxygenase catalyzed oxidation of eicosapentaenoic acid (EPA).
- GC40460 5(S)-HETE 5(S)-HETE is produced by the action of 5-LO on arachidonic acid to give 5(S)-HpETE, followed by reduction of the hydroperoxide.
- GC40829 5(S)-HETE lactone 5(S)-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of 5(S)-HETE.
- GC42479 5(S)-HETrE 5(S)-HETrE is produced by the action of 5-LO when mead acid is the substrate.
- GC41105 5(S)-HpEPE 5(S)-HpEPE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 5-LO on EPA.
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GC40380
5-OxoETE
5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils by a specific dehydrogenase.
- GC41322 5-OxoETE methyl ester 5-OxoETE methyl ester is an esterified form of the polyunsaturated keto acid 5-oxoETE.
- GC40462 8(R)-HETE 8(R)-HETE is biosynthesized by lipoxygenation of arachidonic acid in marine invertebrates such as gorgonian corals and starfish.
- GC41136 8(S),15(S)-DiHETE 8(S),15(S)-DiHETE is formed when 15(S)-HETE is subjected to further oxidation by 15-LO.
- GC40382 8(S)-HEPE 8(S)-HEPE is a monohydroxy fatty acid produced by lipoxygenase oxidation of EPA.
- GC42619 8(S)-HETrE 8(S)-HETrE is a monohydroxy polyunsaturated fatty acid produced by rabbit neutrophil lipoxygenase when dihomo-γ-linolenic acid is used as a substrate.
- GC40464 9(R)-HETE 9(R)-HETE is an enantiomer which makes up 50% of (±)9-HETE.
- GC40465 9(S)-HETE 9(S)-HETE is an enantiomer which makes up 50% of (±)9-HETE.
- GC41146 FOG9 FOG9 is formed through the conjugation of 5-oxoETE with glutathione in a 1,6 Michael addition at C-9.
- GC45023 tetranor-12(R)-HETE Metabolism of 12(R)-HETE in corneal tissue produces predominantly the compound resulting from the loss of four carbon atoms through β-oxidation from C-1.
- GC45024 tetranor-12(S)-HETE 12(S)-HETE is a product of arachidonic acid metabolism through the 12-lipoxygenase pathway.