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Home >> Lipids >> Leukotrienes

Leukotrienes

Products for  Leukotrienes

  1. Cat.No. Product Name Information
  2. GC40430 (±)14(15)-EET

    (±)14(15)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450.

     (±)14(15)-EET Chemical Structure
  3. GC49294 1-(4-Chlorobenzhydryl)piperazine An inactive metabolite of meclizine and chlorcyclizine 1-(4-Chlorobenzhydryl)piperazine Chemical Structure
  4. GC41144 11-trans Leukotriene C4 11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4. 11-trans Leukotriene C4 Chemical Structure
  5. GC41147 11-trans Leukotriene D4 11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. 11-trans Leukotriene D4 Chemical Structure
  6. GC41149 11-trans Leukotriene E4 Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans Leukotriene E4 Chemical Structure
  7. GC41123 12-epi Leukotriene B4 Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes. 12-epi Leukotriene B4 Chemical Structure
  8. GC41096 12-oxo Leukotriene B4 Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway. 12-oxo Leukotriene B4 Chemical Structure
  9. GC41100 14,15-dehydro Leukotriene B4 Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. 14,15-dehydro Leukotriene B4 Chemical Structure
  10. GC41320 14,15-Leukotriene A4 methyl ester 14,15-Leukotriene A4 (14,15-LTA4) methyl ester is an esterified form of 14,15-LTA4, a leukotriene isomer formed from arachidonic acid by 15-lipoxygenase (15-LO) that inhibits LTA4 hydrolase. 14,15-Leukotriene A4 methyl ester Chemical Structure
  11. GC41145 14,15-Leukotriene C4 Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. 14,15-Leukotriene C4 Chemical Structure
  12. GC41148 14,15-Leukotriene D4 14,15-Leukotriene D4 (14,15-LTD4) is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-lipoxygenases (15- and 12-LOs) on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates. 14,15-Leukotriene D4 Chemical Structure
  13. GC41150 14,15-Leukotriene E4 Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. 14,15-Leukotriene E4 Chemical Structure
  14. GC41980 18-carboxy dinor Leukotriene B4 18-carboxy dinor Leukotriene B4 (18-carboxy dinor LTB4) is a β-oxidation metabolite of LTB4. 18-carboxy dinor Leukotriene B4 Chemical Structure
  15. GC42082 20-carboxy Leukotriene B4 20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils. 20-carboxy Leukotriene B4 Chemical Structure
  16. GC41421 20-hydroxy Leukotriene B4 20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils. 20-hydroxy Leukotriene B4 Chemical Structure
  17. GC52413 5-Aminosalicylic Acid-d7 An internal standard for the quantification of 5-aminosalicylic acid 5-Aminosalicylic Acid-d7 Chemical Structure
  18. GC49591 5-oxo Leukotriene B4 A byproduct in 12-oxo LTB4 synthesis 5-oxo Leukotriene B4 Chemical Structure
  19. GC41134 6-trans Leukotriene B4 6-trans LTB4 is produced by the non-enzymatic hydrolysis of LTA4. 6-trans Leukotriene B4 Chemical Structure
  20. GC41135 6-trans-12-epi Leukotriene B4 6-trans-12-epi Leukotriene B4 (LTB4) is a non-enzymatic hydrolysis product of LTA4. 6-trans-12-epi Leukotriene B4 Chemical Structure
  21. GC49836 Benoxaprofen Benoxaprofen (LRCL 3794) is a potent and long-acting anti-inflammatory and antipyretic compound. Benoxaprofen Chemical Structure
  22. GC46105 Butyrolactone II A fungal metabolite Butyrolactone II Chemical Structure
  23. GC43153 CAY10416 Dual cyclooxygenase-2 (COX-2)/5-lipoxygenase (5-LO) inhibitors are potential therapeutic agents for inflammatory diseases and for prostate cancer. CAY10416 Chemical Structure
  24. GC18688 CAY10589 Microsomal Prostaglandin E2 Synthase-1 (mPGES-1), with cyclooxygenase-2 (COX-2), synthesizes PGE2, which is directly involved in signaling during inflammation, fever and pain. CAY10589 Chemical Structure
  25. GC18877 CAY10606 5-Lipoxygenase (5-LO) initiates the synthesis of leukotrienes (LTs) from arachidonic acid, primarily in certain leukocyte populations. CAY10606 Chemical Structure
  26. GC18480 CAY10649 5-Lipoxygenase (5-LO) catalyzes the biosynthesis of leukotrienes, which are involved in a variety of inflammatory responses, including neutrophil chemotaxis, vascular permeability, and smooth muscle contraction. CAY10649 Chemical Structure
  27. GC52307 CAY10790 A CysLT1 receptor antagonist and GPBAR1 agonist CAY10790 Chemical Structure
  28. GC52016 Cetirizine N-oxide An oxidative degradation product of cetirizine Cetirizine N-oxide Chemical Structure
  29. GC43319 CP 24,879 (hydrochloride) Essential fatty acid deficiency symptoms include immune system depression and a general state of inflammatory inhibition. CP 24,879 (hydrochloride) Chemical Structure
  30. GC43453 Diflapolin Diflapolin is a dual inhibitor of 5-lipoxygenase-activating protein (FLAP) and soluble epoxide hydrolase (sEH). Diflapolin Chemical Structure
  31. GC49471 LAMP1 Monoclonal Antibody (Clone Ly1C6) For immunochemical analysis of LAMP1 LAMP1 Monoclonal Antibody (Clone Ly1C6) Chemical Structure
  32. GC40840 Leukotriene A3 methyl ester Biosynthesis of LTA3 occurs from 5,8,11-eicosatrienoic acid via the 5-LO pathway and it is the putative intermediate in the biosynthesis of 3-series leukotrienes. Leukotriene A3 methyl ester Chemical Structure
  33. GC18835 Leukotriene A4 methyl ester Leukotriene A4 (LTA4) is synthesized in mast cells, eosinophils, and neutrophils from arachidonic acid by 5-lipoxygenase (5-LO), which exhibits both lipoxygenase and LTA4 synthase activities. Leukotriene A4 methyl ester Chemical Structure
  34. GC40278 Leukotriene B3 LTB3 is the LTA hydrolase metabolite of LTA3 in the leukotriene biosynthetic pathway. Leukotriene B3 Chemical Structure
  35. GC44052 Leukotriene B4 dimethyl amide LTB4 dimethyl amide is a moderate inhibitor of LTB4-induced degranulation of human neutrophils (Ki = 130 nM) and lysozyme release from rat PMNL. Leukotriene B4 dimethyl amide Chemical Structure
  36. GC44053 Leukotriene B4 Ethanolamide The effects of Leukotriene B4 (LTB4) are mediated by two known receptors, BLT1 and BLT2. Leukotriene B4 Ethanolamide Chemical Structure
  37. GC40631 Leukotriene B4-3-aminopropylamide The effects of leukotriene B4 (LTB4) are mediated by two receptors, BLT1 and BLT2. Leukotriene B4-3-aminopropylamide Chemical Structure
  38. GC47556 Leukotriene B4-d4 A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Leukotriene B4-d4 Chemical Structure
  39. GC49597 Leukotriene B4-d5 An internal standard for the quantification of LTB4 Leukotriene B4-d5 Chemical Structure
  40. GC41107 Leukotriene B5 Leukotriene B5 (LTB5) is a leukotriene with diverse biological activities. Leukotriene B5 Chemical Structure
  41. GC44054 Leukotriene C4 methyl ester Leukotriene C4 (LTC4) is the parent cysteinyl-leukotriene produced by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4. Leukotriene C4 methyl ester Chemical Structure
  42. GC47559 Leukotriene D4-d5 A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Leukotriene D4-d5 Chemical Structure
  43. GC47560 Leukotriene E4-d5 A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications Leukotriene E4-d5 Chemical Structure
  44. GC18845 Leukotriene F4

    LTF4 is a cysteinyl-leukotriene produced in vitro, but not reported to date in vivo.

     Leukotriene F4 Chemical Structure
  45. GC47570 Lipoxygenin An inhibitor of 5-LO Lipoxygenin Chemical Structure
  46. GC47575 Loratadine-d5 An internal standard for the quantification of loratadine Loratadine-d5 Chemical Structure
  47. GC44295 N-acetyl Leukotriene E4 N-acetyl LTE4 is the major inactive metabolite of LTE4 found in bile. N-acetyl Leukotriene E4 Chemical Structure
  48. GC44415 N-methyl Leukotriene C4

    Produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets, leukotriene C4 (LTC4) is the parent cysteinyl leukotriene formed by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4.

     N-methyl Leukotriene C4 Chemical Structure
  49. GC49098 Olsalazine-13C6 An internal standard for the quantification of olsalazine Olsalazine-13C6 Chemical Structure
  50. GC18453 Sulochrin Sulochrin is a fungal metabolite produced by A. Sulochrin Chemical Structure
  51. GC49386 Tepoxalin A dual inhibitor of COX and 5-LO Tepoxalin Chemical Structure
  52. GC45993 Terbutaline A β2-adrenergic receptor agonist Terbutaline Chemical Structure
  53. GC48267 Zileuton-d4 An internal standard for the quantification of zileuton Zileuton-d4 Chemical Structure

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