Lomefloxacin HCl (Synonyms: SC-47111) |
| Catalog No.GC11657 |
Lomefloxacin (SC47111A) hydrochloride is a broad-spectrum quinolone antibiotic, with antimicrobial activity.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 98079-52-8
Sample solution is provided at 25 µL, 10mM.
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Lomefloxacin hydrochloride is a fluoroquinolone antibiotic.Target: AntibacterialLomefloxacin hydrochloride is a bactericidal fluoroquinolone agent with activity against a wide range of gram-negative and gram-positive organisms. The bactericidal action of lomefloxacin results from interference with the activity of the bacterial enzymes DNA gyrase and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. DNA gyrase appears to be the primary quinolone target for gram-negative bacteria. Topoisomerase IV appears to be the preferential target in gram-positive organisms. Interference with these two topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. As a result DNA replication and transcription is inhibited [1].
References:
[1]. http://www.drugbank.ca/drugs/DB00978
Average Rating: 5 (Based on Reviews and 28 reference(s) in Google Scholar.)
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