LYG-202 |
| Catalog No.GC40865 |
LYG-202 is a synthetic flavonoid with anticancer and anti-angiogenic activities.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1175077-25-4
Sample solution is provided at 25 µL, 10mM.
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LYG-202 is a synthetic flavonoid with anticancer and anti-angiogenic activities. It inhibits proliferation of HepG2, MCF-7, HeLa, BGC-823, MDA-MB-435, and HCT116 cancer cells in vitro (IC50s = 4.74-27.70 μM) via induction of apoptosis and dissipation of the mitochondrial membrane potential. LYG-202 reduces tumor growth in S180 sarcoma cell-inoculated mice. It also inhibits VEGF-stimulated human umbilical vein endothelial cells (HUVEC) cell migration and tube formation in vitro and decreases capillary sprouting in isolated rat aortic rings and the chicken chorioallantoic membrane (CAM) model of angiogenesis.
Average Rating: 5 (Based on Reviews and 25 reference(s) in Google Scholar.)
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