|matrix protein (3-15) [Zaire ebolavirus] Catalog No.GP10052|
Sample solution is provided at 25 µL, 10mM.
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|Solubility||≥ 151.6mg/mL in DMSO||Storage||Store at -20°C|
|General tips||For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.|
|Shipping Condition||Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
Matrix protein (3-15) is a peptide of the structure proteins linking the viral envelope with theZaireebolavirus core.
Ebola virus (EBOV) is a member of the family Filoviridae in the order Mononegavirales. It is the causative agent of severe hemorrhagic fevers in human and non-human primates with high case fatality rates.
A role for matrix proteins in the regulation of viral genome replication and transcription has been shown for a number of negative strand RNA viruses. The recent study has shown that both matrix proteins of EBOV, VP40 and VP24, are able to inhibit both viral genome replication and transcription.
1. Hoenen T, Jung S, Herwig A, Groseth A, Becker S (2010) Both matrix proteins of Ebola virus contribute to the regulation of viral genome replication and transcription. Virology 403: 56–66.
2. Dessen A, Viktor V, Dolnik O, Klenk H, Weissenhorn W. Crystal structure of the matrix protein VP 40 from Ebola virus. The EMBO Journal (2010) 19, 4228-4236.