MeOSuc-AAPV-pNA |
| Catalog No.GC44156 |
MeOSuc-AAPV-pNA is a sensitive fluorogenic substrate of human leukocyte and porcine pancreatic elastase.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 70967-90-7
Sample solution is provided at 25 µL, 10mM.
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Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to destroy pathogens. Evaluating these enzymes is helpful to understanding inflammatory autoimmune processes. MeOSuc-AAPV-pNA is a highly sensitive peptide substrate that is hydrolyzed by both human and mouse neutrophil elastase and PR3, but not cathepsin G or chymotrypsin. Enzyme activity can be quantified by colorimetric detection of free p-nitroanilide at 405 nm.
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
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