Meticrane |
| Catalog No.GC11069 |
Peripheral-type benzodiazepine receptor (PBR) inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1084-65-7
Sample solution is provided at 25 µL, 10mM.
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Meticrane is a diuretic. Meticrane inhibits the reabsorption of sodium and chloride ions in the distal convoluted tubule. Meticrane is used to treat essential hypertension.
Meticrane, a thiazide diuretic is highly ranked in the connectivity map (cMap) analysis, and it does not have any known anti-cancer or immune-stimulating effect. Co-treatment with Meticrane significantly enhances treatment efficacy of CTLA-4 blockade[2].
References:
[1]. Rumiko TANAKA, et al. Crystal Structure of Meticrane. ANALYTICAL SCIENCES 2007, VOL. 23.
[2]. Lesterhuis WJ, et al. Network analysis of immunotherapy-induced regressing tumours identifies novel synergisticdrug combinations. Sci Rep. 2015 Jul 21;5:12298.
Average Rating: 5 (Based on Reviews and 7 reference(s) in Google Scholar.)
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