Monohydroxy Melphalan (hydrochloride) (Synonyms: Hydroxymelphalan) |
| Catalog No.GC44243 |
Monohydroxy melphalan is a DNA alkylating agent and a degradation product of melphalan.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Monohydroxy melphalan is a DNA alkylating agent and a degradation product of melphalan . Monohydroxy melphalan is formed by the hydrolysis of melphalan in aqueous solutions, including cell culture medium and human plasma. It increases the level of DNA adducts in ML-1 myeloblastic leukemia cells in a concentration-dependent manner and induces cytotoxicity with an IC50 value of 28.1 μg/ml.
Average Rating: 5 (Based on Reviews and 9 reference(s) in Google Scholar.)
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