MRK 740 |
| Catalog No.GC50576 |
Potent PRDM9 inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2387510-80-5
Sample solution is provided at 25 µL, 10mM.
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Potent PRDM9 histone methyltransferase inhibitor (IC50 = 85 nM for in vitro methylation of H3K4). Displays >100-fold selectivity over other histone methyltransferases. Inhibits H3K4 methylation in cells (IC50 = 0.8 μM).
Allali-Hassani et al (2019) Discovery of a chemical probe for PRDM9. Nat.Commun. 10 5759 PMID:31848333
Review for MRK 740
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
Review for MRK 740
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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