N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid (Synonyms: DANA) |
Catalog No.GC44298 |
N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid (Neu5Ac2en) is a potent neuraminidase (sialidase) inhibitor.
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Cas No.: 24967-27-9
Sample solution is provided at 25 µL, 10mM.
N-acetyl-2,3-dehydro-2-Deoxyneuraminic acid (DANA) is an inhibitor of human neuriminidases (sialidases) NEU1-4 (IC50s = 143, 43, 61, and 74 μM, respectively). In vivo, DANA (30 μL of a 5 mM solution) reduces latency to first seizure and increases seizure duration in a rat model of potassium-induced seizures.
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