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N-nonanoyl-L-Homoserine lactone (Synonyms: C9-HSL, N-nonanoyl-L-HSL)

Catalog No.GC44429

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.

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N-nonanoyl-L-Homoserine lactone Chemical Structure

Cas No.: 177158-21-3

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5mg
$44.00
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10mg
$83.00
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25mg
$201.00
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50mg
$357.00
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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). Regulation of bacterial quorum sensing signaling systems to inhibit pathogenesis represents a new approach to antimicrobial therapy in the treatment of infectious diseases. AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group), and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family. C9-HSL is a rare odd-numbered acyl carbon chain produced by wild-type Erwinia carotovora strain SCC 3193 grown in the nutrient-rich Luria-Bertani Broth (LB) medium.

Chemical Properties

Cas No. 177158-21-3 SDF
Synonyms C9-HSL, N-nonanoyl-L-HSL
Canonical SMILES CCCCCCCCC(=O)N[C@H]1CCOC1=O
Formula C13H23NO3 M.Wt 241.3
Solubility DMF: 20 mg/ml,DMSO: 25 mg/ml,Ethanol: 1.5 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 4.1442 mL 20.7211 mL 41.4422 mL
5 mM 0.8288 mL 4.1442 mL 8.2884 mL
10 mM 0.4144 mL 2.0721 mL 4.1442 mL
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