N-(p-Tosyl)-GPR-pNA (acetate) (Synonyms: N-(p-Tosyl)-Gly-Pro-Arg-p-Nitroanilide, Tos-Gly-Pro-Arg-pNA) |
| Catalog No.GC45667 |
A colorimetric thrombin substrate
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 86890-95-1
Sample solution is provided at 25 µL, 10mM.
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N-(p-Tosyl)-GPR-pNA is a colorimetric substrate for thrombin.1 Thrombin preferentially binds to and cleaves the Gly-Pro-Arg (GPR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of thrombin activity.
|1. Abildgaard, U., Lie, M., and •deg•rd, O.R. Antithrombin (heparin cofactor) assay with "new" chromogenic substrates (S-2238 and Chromozym TH). Thromb. Res. 11(4), 549-553 (1977).
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