Home>>N-(p-Tosyl)-GPR-pNA (acetate)
N-(p-Tosyl)-GPR-pNA (acetate) Catalog No.GC45667

A colorimetric thrombin substrate

Size Price Stock Qty
25mg
$168.00
In stock
50mg
$318.00
In stock
100mg
$570.00
In stock
250mg
$1,256.00
In stock

Customer Review

Based on customer reviews.

Tel: (626) 353-8530 Email: sales@glpbio.com

Sample solution is provided at 25 µL, 10mM.

Quality Control

Quality Control & SDS

View current batch:

Chemical Properties

Cas No. 86890-95-1 SDF Download SDF
Synonyms N/A
Chemical Name N/A
Canonical SMILES CC1=CC=C(S(NCC(N2CCC[C@H]2C(N[C@@H](CCCNC(N)=N)C(NC3=CC=C([N+]([O-])=O)C=C3)=O)=O)=O)(=O)=O)C=C1.OC(C)=O
Formula C26H34N8O7S.C2H4O2 M.Wt 662.7
Solubility DMF: 20mg/mL,DMSO: 3mg/mL,PBS (pH 7.2): 3mg/mL Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
  • Molarity Calculator

  • Dilution Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

Calculate

Background

N-(p-Tosyl)-GPR-pNA is a colorimetric substrate for thrombin.1 Thrombin preferentially binds to and cleaves the Gly-Pro-Arg (GPR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of thrombin activity.

|1. Abildgaard, U., Lie, M., and •deg•rd, O.R. Antithrombin (heparin cofactor) assay with "new" chromogenic substrates (S-2238 and Chromozym TH). Thromb. Res. 11(4), 549-553 (1977).