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N6-Methyladenine (Synonyms: NSC 11580)

Catalog No.GC40496

N6-Methyladenine is a modified purine that is commonly found in genomes of prokaryotes, protists, and plants.

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N6-Methyladenine Chemical Structure

Cas No.: 443-72-1

Size Price Stock Qty
50mg
$67.00
In stock
100mg
$121.00
In stock
250mg
$268.00
In stock
500mg
$401.00
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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

N6-Methyladenine is a modified purine that is commonly found in genomes of prokaryotes, protists, and plants. It is less common in higher eukaryotes and extremely rare in mammals. Like methylation of other DNA residues, N6-methyladenine represents an epigenetic modification that can affect diverse DNA functions, including replication, repair, and expression.

Chemical Properties

Cas No. 443-72-1 SDF
Synonyms NSC 11580
Canonical SMILES CNC(NC=N1)=C2C1=NC=N2
Formula C6H7N5 M.Wt 149.2
Solubility DMF: 2 mg/ml,DMSO: 1 mg/ml,Ethanol: 5 mg/ml,PBS (pH 7.2): 2 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 6.7024 mL 33.5121 mL 67.0241 mL
5 mM 1.3405 mL 6.7024 mL 13.4048 mL
10 mM 0.6702 mL 3.3512 mL 6.7024 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 27 reference(s) in Google Scholar.)

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