Naftifine-d3 (hydrochloride) |
| Catalog No.GC45997 |
An internal standard for the quantification of naftifine
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1246833-81-7
Sample solution is provided at 25 µL, 10mM.
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Naftifine-d3 is intended for use as an internal standard for the quantification of naftifine by GC- or LC-MS. Naftifine is an allylamine compound that blocks ergosterol biosynthesis in fungi by inhibiting squalene epoxidase (Ki = 1.1 μM for C. albicans epoxidase).1
|1. Ryder, N.S., and Dupont, M.C. Inhibition of squalene epoxidase by allylamine antimycotic compounds. A comparative study of the fungal and mammalian enzymes. Biochem. J. 230(3), 765-770 (1985).
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