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Nervonic Acid methyl ester (Synonyms: Methyl Nervonate)

Catalog No.GC44365

Nervonic acid (24:1n-9) is a very long chain fatty acid produced by elongation of oleic acid (18:1n-9) and derived from erucic acid (22:1n-9).

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Nervonic Acid methyl ester Chemical Structure

Cas No.: 2733-88-2

Size Price Stock Qty
50mg
$69.00
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100mg
$131.00
In stock
500mg
$548.00
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Sample solution is provided at 25 µL, 10mM.

Description of Nervonic Acid methyl ester

Nervonic acid (24:1n-9) is a very long chain fatty acid produced by elongation of oleic acid (18:1n-9) and derived from erucic acid (22:1n-9) . It is enriched in nervous tissue and is particularly abundant in sphingolipids, such as sphingomyelin in the myelin sheath of nerve fibers. Nervonic acid is poorly produced in demyelinating disorders, including multiple sclerosis and adrenoleukodystrophy, suggesting that dietary supplementation may be beneficial. Nervonic Acid methyl ester is an ester version of the free acid which may be more suitable for the formulation of fatty acid-containing diets and dietary supplements.

Chemical Properties of Nervonic Acid methyl ester

Cas No. 2733-88-2 SDF
Synonyms Methyl Nervonate
Canonical SMILES CCCCCCCC/C=C\CCCCCCCCCCCCCC(OC)=O
Formula C25H48O2 M.Wt 380.7
Solubility DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 100 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Nervonic Acid methyl ester

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1 mg 5 mg 10 mg
1 mM 2.6267 mL 13.1337 mL 26.2674 mL
5 mM 0.5253 mL 2.6267 mL 5.2535 mL
10 mM 0.2627 mL 1.3134 mL 2.6267 mL
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In vivo Formulation Calculator (Clear solution) of Nervonic Acid methyl ester

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 21 reference(s) in Google Scholar.)

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