Olutasidenib (FT-2102) (Synonyms: FT-2102) |
| Catalog No.GC31874 |
Olutasidenib (FT-2102) (FT-2102) is a highly potent, orally active, brain penetrant and selective inhibitor of mutant Isocitrate dehydrogenase 1 (IDH1), with IC50 values of 21.2 nM and 114 nM for IDH1- R132H and IDH1- R132C, respectively .
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Cas No.: 1887014-12-1
Sample solution is provided at 25 µL, 10mM.
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Olutasidenib is a highly potent, selective inhibitor of mutant Isocitrate dehydrogenase (IDH)1 that could be used in the treatment of acute myeloid leukemia.
[1]. JM Watts, et al. A phase 1 dose escalation study of the IDH1m inhibitor, FT-2102, in patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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