Palmitelaidic Acid-d13 (Synonyms: C16:1(9E)-d13, 9-trans-Hexadecenoic Acid-d13) |
| Catalog No.GC47858 |
A neuropeptide with diverse biological activities
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2692623-91-7
Sample solution is provided at 25 µL, 10mM.
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Palmitelaidic acid-d13 is intended for use as an internal standard for the quantification of palmitelaidic acid by GC- or LC-MS. Palmitelaidic acid is a trans isomer of palmitoleic acid and dietary fatty acid that has been found in dairy fat products and various partially hydrogenated oils.1,2 It decreases nitric oxide (NO) production and levels of soluble E-selectin in isolated human aortic endothelial cells (HAECs) when used at a concentration of 20 µM.1 Palmitelaidic acid (49 µM) inhibits Sendai virus-induced hemolysis of isolated human erythrocytes.3 Increased serum levels of palmitelaidic acid are associated with higher levels of LDL, but lower levels of triglycerides, fasting insulin, blood pressure, and incidence of diabetes.2
1.Livingstone, K.M., Givens, D.I., Jackson, K.G., et al.Comparative effect of dairy fatty acids on cell adhesion molecules, nitric oxide and relative gene expression in healthy and diabetic human aortic endothelial cellsAtherosclerosis234(1)65-72(2014) 2.Mozaffarian, D., de Oliveira Otto, M.C., Lemaitre, R.N., et al.trans-Palmitoleic acid, other dairy fat biomarkers, and incident diabetes: The multi-ethnic study of atherosclerosis (MESA)Am. J. Clin. Nutr.97(4)854-861(2013) 3.MacDonald, R.C., Ore, V.D., and MacDonald, R.I.Inhibition of sendai virus-induced hemolysis by long chain fatty acidsVirology134(1)103-117(1984)
| Cas No. | 2692623-91-7 | SDF | |
| Synonyms | C16:1(9E)-d13, 9-trans-Hexadecenoic Acid-d13 | ||
| Canonical SMILES | [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])/C=C/CCCCCCCC(O)=O | ||
| Formula | C16H17D13O2 | M.Wt | 267.5 |
| Solubility | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: >50mg/ml | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 3.7383 mL | 18.6916 mL | 37.3832 mL |
| 5 mM | 0.7477 mL | 3.7383 mL | 7.4766 mL |
| 10 mM | 0.3738 mL | 1.8692 mL | 3.7383 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >99.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 35 reference(s) in Google Scholar.)
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