Home>>PAR4 (1-6) (mouse) (trifluoroacetate salt)

PAR4 (1-6) (mouse) (trifluoroacetate salt) (Synonyms: GYPGKF, H-Gly-Tyr-Pro-Gly-Lys-Phe-OH)

Catalog No.GC40156

PAR4 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 4 (PAR4; EC50 = 30 μM in Xenopus oocytes expressing human PAR4 receptors) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse PAR4 and residues 60-65 of the full-length sequence.

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PAR4 (1-6) (mouse) (trifluoroacetate salt) Chemical Structure

Size Price Stock Qty
1mg
$60.00
In stock
5mg
$271.00
In stock
10mg
$479.00
In stock
25mg
$1,051.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

PAR4 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 4 (PAR4; EC50 = 30 μM in Xenopus oocytes expressing human PAR4 receptors) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse PAR4 and residues 60-65 of the full-length sequence. It induces calcium release in wild-type and PAR3-/- mouse platelets and in human platelets but has no activity in Xenopus oocytes expressing human PAR1. PAR4 (1-6) also triggers [3H]inositol phosphate release from KOLF cells expressing human PAR4.

Chemical Properties

Cas No. SDF
Synonyms GYPGKF, H-Gly-Tyr-Pro-Gly-Lys-Phe-OH
Canonical SMILES OC(C(F)(F)F)=O.[H]NCC(N[C@H](C(N1CCC[C@H]1C(NCC(N[C@@H](CCCCN)C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)CC3=CC=C(O)C=C3)=O
Formula C33H45N7O8 • XCF3COOH M.Wt 667.8
Solubility Water: 1 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 1.4975 mL 7.4873 mL 14.9745 mL
5 mM 0.2995 mL 1.4975 mL 2.9949 mL
10 mM 0.1497 mL 0.7487 mL 1.4975 mL
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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 5 reference(s) in Google Scholar.)

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