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PEO-IAA (2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid) Catalog No.GC30168

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Sample solution is provided at 25 µL, 10mM.

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Chemical Properties

Cas No. 6266-66-6 SDF Download SDF
Synonyms N/A
Chemical Name N/A
Canonical SMILES O=C(O)C(CC(C1=CC=CC=C1)=O)C2=CNC3=C2C=CC=C3
Formula C18H15NO3 M.Wt 293.32
Solubility DMSO : ≥ 150 mg/mL (511.39 mM) Storage Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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PEO-IAA is an indole-3-acetic acid (IAA) antagonist. PEO-IAA is an auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs).

PEO-IAA is also an α-alkyl-IAA, and shows more potent anti-auxin activity in auxin-responsive gene expression and in the cell division and elongation pathway that is mediated via SCFTIR1/AFBs. PEO-IAA suppresses not only the expression of an auxin-responsive ZmSAUR2 gene, but also gravitropic curvature. PEO-IAA blocks the auxin response in Arabidopsis, rice, moss and maize[1].

[1]. Nishimura T, et al. Differential downward stream of auxin synthesized at the tip has a key role in gravitropic curvature via TIR1/AFBs-mediated auxin signaling pathways. Plant Cell Physiol. 2009 Nov;50(11):1874-85.