Phentolamine Mesylate |
| Catalog No.GC16291 |
Alpha 1/2-blocking agent
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 65-28-1
Sample solution is provided at 25 µL, 10mM.
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Phentolamine mesylate is a competitive, reversible α-adrenoceptor antagonist with an IC50 between 5 and 30 nM.
References:
[1]. Giussani, D.A., et al., Alpha 1- and alpha 2-adrenoreceptor actions of phentolamine and prazosin on breathing movements in fetal sheep in utero. J Physiol, 1995. 486 ( Pt 1): p. 249-55.
[2]. Saeed, M., et al., Alpha-adrenoceptor blockade by phentolamine causes beta-adrenergic vasodilation by increased catecholamine release due to presynaptic alpha-blockade. J Cardiovasc Pharmacol, 1982. 4(1): p. 44-52.
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